摘要：<正>In mammalians,the state of a somatic cell can be reversed from the terminal state to the totipo...<正>In mammalians,the state of a somatic cell can be reversed from the terminal state to the totipotent state by means of somatic cell nuclear transfer(SCNT)(Gurdon,1962)or induced pluripotent stem cells(iPSCs)(Takahashi and Yamanaka,2006).The DNA methylation and transcriptome profiles of embryonic stem cells(ESCs)derived from SCNT embryos(NT-ESCs)correspond closely显示全部
