作　　者： (李兰芳）; (翟明）; (赵莹）; (林大都）; ;

机构地区： 嘉应学院医学院

出　　处： 《嘉应学院学报》 2022年第3期34-39,共6页

摘　　要： 研究沙田柚含片的处方及制备工艺.以口感、外观、硬度、崩解时限为考察指标,通过单因素实验和正交试验,优选出沙田柚含片的处方,并对含片进行质量评价.结果表明:柚子浸膏25%、甘露醇21.8%、乳糖43.6%、甜菊糖苷3%、硬脂酸镁1.5%、橘红3%、罗汉果2%和适量无水乙醇,采用湿法制粒,压片,制得的沙田柚含片口感好、色泽均匀、硬度及崩解时限符合《中国药典》要求,制备工艺简单可行,为沙田柚的开发利用提供了参考依据. The prescription and preparation technology of Shatian pomelo buccal tablets were studied.Taking taste,appearance,hardness and disintegration time as indexes,the prescription of Shatian pomelo buccal tablets was optimized by single factor experiment and orthogonal experiment,and the quality of buccal tablets was evaluated.The results showed that:grapefruit extract25%,mannitol 21.8%,lactose 43.6%,stevioside 3%,magnesium stearate 1.5%,Orange 3%,Siraitia grosvenorii 2%and an appropriate amount of absolute ethanol,wet granulation and tablet pressing were used to prepare Shatian pomelo buccal tablets with good taste,uniform color,hardness and disintegration time,which met the requirements of Chinese Pharmacopoeia,and the preparation process was simple and feasible.It provides a reference basis for the development and utilization of Shatian pomelo.

关 键 词： 柚子 含片 正交试验 制备工艺

领　　域： [轻工技术与工程—食品科学] [轻工技术与工程—食品科学与工程]