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镍钛合金支架与双蒂带状肌筋膜瓣修复犬喉缺损实验研究
Experimental study on the repair of canine laryngeal defect by nickel-titanium alloy stent and double-pedicled fascial flap

作  者: ();

机构地区: 深圳市人民医院

出  处: 《山东大学耳鼻喉眼学报》 2018年第6期22-25,共4页

摘  要: 目的探索镍钛合金支架与双蒂带状肌筋膜瓣联合修复重建犬喉支架和组织单侧大范围缺损的方法和效果。方法采用比格犬10只,切除右侧甲状软骨板前1/2以及相应的声室带组织,将镍钛合金支架与右侧甲状软骨板残端固定,右侧双蒂带状肌筋膜瓣翻入喉腔与声室带残端缝合,完全包裹支架。术后定期观察喉部创面以及镍钛合金支架与周围组织的愈合情况。结果 10只实验犬,1只广泛皮下和纵膈气肿死亡,9只术后存活良好,无呼吸困难。术后第7天、14天、1个月喉镜检查,喉部创面有少量肉芽组织增生,术后3个月、6个月增生的肉芽组织消退,喉腔创面光滑。结论镍钛合金支架与双蒂带状肌筋膜瓣联合修复重建犬喉支架和组织大范围缺损,只要手术方式选择得当,可以取得比较好的效果。 Objective To explore the outcome of repairing a laryngeal stent and unilateral large-scale tissue defect with a nickel-tita- nium alloy stent and double-strap ribbon myofascial flap in beagle dogs.Methods Ten beagle dogs were used.One-half of the right thyroid cartilage plate and corresponding acoustic chamber tissue were removed.A nickel-titanium alloy stent was fixed to the right thyroid cartilage plate stump.The.right pedicle ribbon myofascial flap was placed into the throat cavity and sutured to the acoustic chamber tissue and thyroid cartilage stump,completely wrapping the stent.After the operation,the wounds on the laryngeal surface and healing of the nickel-titanium alloy stent into the surrounding tissue were regularly observed.Results Of the 10 experimental dogs,1 died of extensive subcutaneous and mediastinal emphysema.Nine dogs recovered well without breathing difficulties.At 1, 7,and 14 months after the operation,there was a small amount of granulation in the larynx wound,which disappeared in March and June;subsequently,the wound surface in the laryngeal cavity was smooth.Conclusion Nickel-titanium alloy stents and double- strapped myofascial flaps can be used to repair and reconstruct a wide range of defects in canine laryngeal stents and tissues..When the surgical method is properly selected,superior results can be obtained.

关 键 词: 喉重建 动物实验 镍钛合金支架 双蒂带状肌筋膜瓣

领  域: []

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