作　　者： (）;

机构地区： 广东医科大学附属第二医院

出　　处： 《中华保健医学杂志》 2019年第2期140-142,共3页

摘　　要： 目的评价内镜逆行胰胆管造影术(ERCP)治疗急性胆源性胰腺炎(ABP)伴有血压增高患者的疗效及对炎症反应的影响。方法选取2015年3月～2017年3月广东医科大学附属第二医院收治的146例ABP伴血压增高患者按随机数表法分为对照组(73例)和观察组(73例),对照组患者采用常规治疗,观察组患者加用ERCP术,比较两组临床症状缓解时间、临床疗效、生化指标、炎症反应及死亡率。结果观察组体温正常时间、腹痛缓解时间、肛门排气时间、黄疸消退时间均少于对照组,差异有统计学意义(P <0.05);观察组总有效率为98.6%,明显高于对照组的89.0%,差异有统计学意义(P <0.05);与对照组相比,观察组血清IL-8、CRP、TNF-α含量及生化指标较优,差异有统计学意义(P <0.05)。两组均无患者死亡。结论 ERCP用于ABP伴有血压增高患者安全有效,且可降低患者炎症反应。 Objective To observe the curative effect of ERCP for acute biliary pancreatitis(ABP) complicated with hypertension and the impact on inflammation. Methods 146 cases were randomly divided into control group(73 cases) and study group(73 cases),the control group received traditional treatment,the study group received endoscopic retrograde cholangiopancreatography(ERCP) additionally. The recovery time of clinical symptoms,the clinical efficiency,biochemical indicator,inflammation responses and death rate was compared. Results Compared with open surgery group,for study group,the time of body temperature returned to normal,the abdominal pain relief time,anal exhaust time,jaundice subsided time was shorter (P < 0.05). The clinical efficiency in study group was 98.6%,which was much higher than that in control group of 89.0%(P < 0.05). The levels of IL-8,CRP and TNF-α,biochemical indicator were better in study group(P < 0.05). The other indexes were similar. Conclusion ERCP is effective and safe for ABP complicated with hypertension,and could reduce inflammation.

关 键 词： 高血压 急性胆源性胰腺炎 疗效 炎症

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