作　　者： (）;

机构地区： 怀集县人民医院

出　　处： 《中国医药科学》 2018年第11期130-132,共3页

摘　　要： 目的探析联合检测C反应蛋白、降钙素原、血沉对诊断慢性阻塞性肺疾病急性加重期细菌感染的临床价值。方法回顾性分析2015年1月~2017年7月我院收治的100例慢性阻塞性肺疾病患者,采用随机数字表法分为加重期组(50例慢性阻塞性肺疾病急性加重期患者)和稳定期组(50例慢性阻塞性肺疾病稳定期患者),选取同期健康体检者50例作为对照组。对三组受检者的CRP、PCT、ESR进行检测,并统计比较三组受检者的检测结果。结果加重期组CRP、PCT、ESR水平相比于对照组、稳定期组明显更高,差异有统计学意义(P<0.05)。CRP+PCT+ESR联合诊断AECOPD的敏感度、特异度相比于CRP、PCT、ESR单一诊断明显更高,差异有统计学意义(P<0.05)。结论 CRP、PCT、ESR联合检测对诊断AECOPD的临床价值非常高,特别是PCT检测,可作为诊断AECOPD细菌感染的重要指标,值得进一步应用与推广。 Objective To explore the clinical value of combined detection of C reactive protein(CRP),calcitonin(PCT)and erythrocyte sedimentation rate(ESR)in the diagnosis of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)bacterial infection.Methods A retrospective analysis of 100 patients with chronic obstructive pulmonary disease(COPD)in our hospital from January 2015 to July 2017 was divided into the aggravation group(50 cases of acute exacerbation of chronic obstructive pulmonary disease)and the stable period group(50 patients with stable stage of chronic obstructive pulmonary disease),and 50 patients with medical examiners at the same period was used as the control group.The CRP,PCT and ESR of the three groups were tested,and the results of the three groups were compared.Results The levels of CRP,PCT and ESR in the aggravation group were significantly higher than those in the control group and the stable period group,the difference was statistically significant(P<0.05).The sensitivity and specificity of combined detection of CRP,PCT and ESR in diagnosis of AECOPD were significantly higher than those in single diagnosis of CRP,PCT and ESR,the difference was statistically significant(P<0.05).Conclusion The combined detection of CRP,PCT and ESR has high clinical value for the diagnosis of AECOPD,especially the PCT detection,which can be used as an important indicator for the diagnosis of AECOPD bacterial infection.It is worth further application and popularization.

关 键 词： 反应蛋白 降钙素原 血沉 慢性阻塞性肺疾病急性加重期

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