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Foley尿管、缩宫素及米索前列醇用于足月妊娠促宫颈成熟的效果比较
Comparison on the effect of Foley catheter, oxytocin and misoprostol for cervical ripening in term pregnancy

作  者: ; ;

机构地区: 东莞市桥头医院

出  处: 《海南医学》 2019年第3期333-335,共3页

摘  要: 目的对比Foley尿管、缩宫素及米索前列醇用于足月妊娠促宫颈成熟的效果,以期为临床上促宫颈成熟措施的选择提供依据。方法选择2018年1~10月期间在东莞市桥头医院妇产科住院待产者120例为研究对象,根据随机数表法将患者随机分为A组、B组、C组,每组40例,A组釆用Foley尿管小水囊、B组采用米索前列醇、C组采用缩宫素促宫颈成熟治疗,比较三组孕妇促宫颈成熟效果,同时比较阴道分娩者的24 h分娩率、引产至临产和分娩时间、总产程、产后出血量,以及新生儿出生Apgar评分、体质量和产褥感染等情况。结果 A组、B组孕妇的促宫颈成熟有效率(85.00%和90.00%)和阴道分娩率(75.00%和80.00%)比较差异均无统计学意义(P>0.05),但是A组、B组孕妇的促宫颈成熟有效率和阴道分娩率明显高于C组的50.00%和42.50%,差异均有统计学意义(P<0.05);B组孕妇引产24 h内分娩率、引产至临产时间、引产至分娩时间明显优于A组,A组优于C组,差异均有统计学意义(P<0.05);三组产妇总产程及产后出血量比较,差异均无统计学意义(P>0.05);三组产妇均未发生产褥感染;三组新生儿体质量、新生儿Apgar评分比较差异均无统计学意义(P>0.05)。结论 Foley尿管、米索前列醇用于足月妊娠促宫颈成熟均可取得满意的效果,其中米索前列醇起效更加快速,可以有效缩短产程。 Objective To compare the effects of Foley catheter, oxytocin and misoprostol in promoting cervical ripening in full-term pregnancy, so as to provide evidence for the selection of clinical measures to promote cervical ripening. Methods From January 2018 to October 2018, 120 patients in Department of Obstetrics and Gynecology,Dongguan Qiaotou Hospital were randomly divided into group A, group B and group C, each with 40 patients, to receive catheter, misoprostol, and oxytocin, respectively, to promote cervical maturation. The effects of promoting cervical maturation were compared among the three groups, and the 24 hour delivery rate of vaginal delivery, the time from induced labor to labor and delivery, total labor process, postpartum hemorrhage, Apgar score, body weight, puerperal infection were also compared. Results There was no significant difference between group A and group B in effective rate for cervical ripening(85.00% and 90.00%) and vaginal delivery rate(75.00% and 80.00%), which significantly higher than50.00% and 42.50% in group C(P<0.05). The 24 hour delivery rate, the time from induced labor to labor, and the time from induced labor to delivery were significantly better in group B than group A, and also in group A than group C(P<0.05). There was no significant difference in the total labor and postpartum hemorrhage among the three groups(P>0.05). There was no puerperal infection among the three groups, and no significant difference was found in body mass and neonatal Apgar score among the three groups(P>0.05). Conclusion Foley catheter and misoprostol can be used to promote cervical ripening in full-term pregnancy with satisfactory results. Misoprostol has a faster onset and can effectively shorten the labor process.

关 键 词: 尿管 缩宫素 米索前列醇 足月妊娠 宫颈成熟

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