作　　者： ; ;

机构地区： 北京协和医院

出　　处： 《中国卫生经济》 2018年第12期87-90,共4页

摘　　要： 目的:评估应用氧化再生纤维素防粘连膜(INTERCEED)对比单纯手术在预防妇产科手术后粘连长期效果的经济性。方法:采用卫生经济学方法,建立Markov-决策树模型,比较INTERCEED和单纯手术增量成本效果比(ICER)。成本和临床数据来源于文献或临床医生调查。模型评估的最长观察期为5年。结果:相比单纯手术组,子宫肌瘤剔除术和卵巢手术在观察期为两年时,ICER値分别为29 042.93和3 144.52元/QALY;为极具有成本-效果的干预措施。妇科其他术式和剖宫产不同频次,INTERCEED组在所有观察期,均是具有绝对优势的干预措施。结论:妇产科手术中使用INTERCEED相对单纯手术是一种能够节约患者长期医疗费用的防粘连措施。 Objective: To evaluate the cost-utility of long-term effect in using INTERCEED to preventing adhesion after gynecologic surgeries. Methods: Based on health economics, a Markov-decision tree model was constructed to compare the increasing cost effect ratio(ICER) of INTERCEED and surgery. The models were obtained from published literature or clinical experts survey. The model calculated the ICER in a 5-year horizon. Results: Compared to no INTERCEED group, with 2 years of observation period, the ICER for the INTERCEED in myomectomy and ovarian surgery was 29 042.93 yuan/QALY and 31 444.52 yuan/QALY respectively. The intervention measurement proved its cost-effectiveness. For gynecologic surgeries and cesarean, the INTERCEED group was the advantaged prevention measurement in all the observation periods. Conclusion: INTERCEED group has better long-term efficacy and lower overall costs compared with no INTERCEED group.

关 键 词： 妇产科手术 术后粘连 氧化再生纤维素 成本 效用分析

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