作　　者： ; ; ;

机构地区： 广州医科大学

出　　处： 《中国医药科学》 2017年第22期41-43,50,共4页

摘　　要： 目的观察妊娠合并血小板减少症的病因及其对母婴分娩结局的影响。方法选取2015年5月~2017年5月我院收治的125例妊娠合并血小板减少症患者为研究对象,将其设为观察组,根据患者的血小板计数将其分为轻度组(n=48)、中度组(n=47)和重度组(n=30),并选取同期于我院收治的120例血小板计数正常孕妇为对照组。分析病因,对两组研究对象的剖宫产率、产后出血率、新生儿窒息等指标进行对比,并对观察组内的母婴分娩结果进行回顾性分析。结果妊娠合并血小板减少症的病因主要为妊娠相关性血小板减少症、特发性血小板减少性紫癜;两组孕妇在剖宫产率方面无明显差异(P>0.05);观察组的产后出血率和新生儿窒息率明显高于对照组(P<0.05);观察组中,轻度组的阴道分娩率高于其余两组,产后出血率及新生儿窒息率低于重度组(P<0.05);三组在新生儿贫血率和早产率上相比有显著差异(P<0.05),均无产褥期感染、颅内感染及死亡。结论妊娠合并血小板减少症与早产、贫血、产妇产后出血以及新生儿血小板减少存在密切联系,患者血小板数量越少则合并妊娠期疾病的可能性越高,对新生儿的影响越大,故在临床上需要引起高度重视。 Objective To analyze of observationof the etiology of pregnancy associated thrombocytopenia and its influence on maternal and child delivery outcomes. Methods 125 cases of pregnancy with thrombocytopenia patients from May 2015 to May 2017 in our hospital were selected as the research object, and set as observation group.The patients were divided into mild group （n=48）, moderate group （n=47） and severe group （n=30） according to the platelet count,and 120 cases of normal platelet count pregnant women were selected as control group.Analysing of the cause of disease, cesarean section rate, postpartum hemorrhage rate, neonatal asphyxia and other indicators of the patients in two groups were compared. Results The main causes of thrombocytopenia in pregnancy were pregnancy associated thrombocytopenia and idiopathic thrombocytopenic purpura.There was no significant difference in cesarean section rate between the two groups （P〈 0.05）.The postpartum hemorrhage rate and neonatal asphyxia rate in the observation group were significantly higher than those in the control group （P 〈 0.05）.In the observation group, the vaginal delivery rate of mild group was higher than the other two groups, the rate of postpartum hemorrhage and neonatal asphyxia rate was lower than that of severe group （P 〈 0.05）.There were significant differences between the three groups in neonatal anemia rate and preterm birth rate （P 〈 0.05）. There were no puerperal infection, intracranial infection and death. Conclusion Pregnancy associated tl^rombocytopenia is associated with preterm birth, anemia, postpartum hemorrhage, and neonatal thrombocytopenia. The less the number of platelets, the higher the possibility of pregnancy associated diseases, the greater the impact on the newborn, so it is need to cause great attention in clinical.

关 键 词： 妊娠 血小板减少症 母婴分娩结局 新生儿结局

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