作　　者： ; ; ; ;

机构地区： 广州医科大学

出　　处： 《国际呼吸杂志》 2019年第20期1576-1580,共5页

摘　　要： 世界卫生组织(WHO)公布截止2018年11月,人H7N9共5波疫情总死亡人数615人,其中第5波人H7N9死亡人数达290例。突如其来的第5波人H7N9疫情比以往4波更加严重,爆发速度更迅猛,覆盖城市范围更广泛,且其对哺乳类动物的致病性也有所增强。因此,充分了解H7N9的流行特征以及病毒进化等特点,可为该疫情的监测、诊断、预防以及治疗等方面提供坚实的理论基础。本文主要不仅总结了第5波H7N9病毒学特征,还包括了动物特征及临床特征等,并对比前4波疫情情况进行分析,可为未来H7N9病毒感染进行风险评估。 World Health Organization announced that the total number of deaths in five-wave epidemic of H7N9 was 615,of which 290 were the fifth wave of H7N9 deaths until Noverber 2018.The sudden fifth wave H7N9 epidemic is more serious than the previous four waves,the explosion was more rapid,covering a wider range of cities,and its pathogenicity to mammals has also enhanced.Therefore,a full understanding of the epidemiological characteristics of H7N9 and the evolution of the virus can provide a solid theoretical foundation for the monitoring,diagnosis,prevention and treatment of the epidemic.This paper mainly reviews the virological characteristics,animal characteristics,clinical features of the fifth wave of H7N9 to assess future risks comparing the situation of the first four waves.

关 键 词： 病毒学特征 风险评估

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