作　　者： ; ; ;

机构地区： 广东省普宁市人民医院

出　　处： 《国际脑血管病杂志》 2020年第2期99-104,共6页

摘　　要： 目的评估一期血管内介入治疗颅内多发动脉瘤的安全性和有效性。方法回顾性分析2010年1月1日至2018年1月1日在广东省普宁市人民医院接受一期血管内介入治疗的颅内多发动脉瘤患者的资料。评估出院和随访时临床和血管造影结果。结果共纳入16例接受一期血管内治疗的多发性颅内动脉瘤患者。其中,男性6例,女性10例;年龄(49.5±17.2)岁;5例为颅内动脉瘤破裂导致的蛛网膜下腔出血患者,其中3例世界神经外科医师联盟分级Ⅰ级,2例Ⅱ级。共35个动脉瘤,13例患者有2个颅内动脉瘤,3例患者有3个颅内动脉瘤。后循环动脉瘤3个,前循环动脉瘤32个;动脉瘤直径为(6.9±3.3)mm。15个动脉瘤行单纯弹簧圈栓塞,20个动脉瘤行支架辅助弹簧圈栓塞,未发生治疗相关并发症。13例患者得到临床随访资料,共随访(17.7±6.4)个月(范围6~28个月),12例改良Rankin量表评分0分,1例6分(死于再出血)。10例患者的23个动脉瘤得到影像学随访资料,随访(10.2±3.3)个月(范围6~15个月),20个未复发,3个(3/23,13.0%)复发。结论一期血管内栓塞治疗对于多发性颅内动脉瘤是一种安全和有效的治疗方法,应进一步评估其远期转归。 Objective To evaluate the safety and effectiveness of one-stage intravascular interventional treatment for intracranial multiple aneurysms.Methods From January 1,2010 to January 1,2018,the data of patients with multiple intracranial aneurysm undergoing one-stage endovascular embolization in the Department of Nerurosurgery,Puning People's Hospital,Guangdong Province were analyzed retrospectively.The clinical and angiographic findings at discharge and follow-up were evaluated.Results A total of 16 patients with multiple intracranial aneurysms received one-stage endovascular treatment were enrolled.Among them,10 were females and 6 were males;their age was 49.5±17.2 years;5 patients were subarachnoid hemorrhage caused by rupture of intracranial aneurysms,three of them were classified as gradeⅠand two were classified as gradeⅡby the World Federation of Neurosurgical Societies(WFNS).There are a total of 35 aneurysms,13 patients had 2 intracranial aneurysms,and 3 had 3 intracranial aneurysms.There were 3 posterior circulation aneurysms and 32 anterior circulation aneurysms;the mean diameter of the aneurysms was 6.9±3.3 mm.Fifteen aneurysms were only treated with coil embolization,and 20 aneurysms were treated with stent-assisted coil embolization.No treatment-related complications occurred.Thirteen patients were followed up for a total of 17.7±6.4 months(range,6-28 months).The modified Rankin Scale score of 12 patients was 0 and 1 was 6(died of rebleeding).The imaging follow-up data of 23 aneurysms in 10 patients were obtained.They were followed up for 10.2±3.3 months(range,6-15 months),20 aneurysms did not recur and 3(3/23,13.0%)recurred.Conclusions One-stage endovascular embolization is a safe and effective treatment for multiple intracranial aneurysms,and its long-term outcome should be further evaluated.

关 键 词： 颅内动脉瘤 栓塞 治疗性 治疗结果

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