作　　者： ;

机构地区： 广州市白云区疾病预防控制中心

出　　处： 《预防医学论坛》 2019年第10期754-755,759,共3页

摘　　要： 目的对1例感染不明的恶性疟病例进行实验室检测分析并确诊。方法2017年10月18日收集该病例临床资料,并开展流行病学溯源调查,采集患者和疑似传染源(供血者)的血样,采用血片镜检、快速疟疾诊断试剂条(RDT)和PCR三种方法进行疟疾病原检测。结果该患者无疟疾流行区外出史,因治疗白血病有大量输血史。输血后出现畏寒、发热症状和外周血涂片镜检诊断为恶性疟原虫感染,RDT检测恶性疟原虫阳性。经溯源调查,疑似传染源的供血者为非洲籍留学生,在献血前曾有疟疾病史,PCR检测供血者血站留存血样恶性疟原虫阳性。结论该病例为输血性恶性疟,因输入非洲籍留学生血液而感染恶性疟。 Objective To conduct laboratory detection and diagnose a case of falciparum malaria with unknown origin.Methods Clinical data of the case was collected in October 18,2017and the epidemiological investigation was conducted to trace the origin.The blood samples of the patient and the suspected infection source(blood donor)were detected by microscopy,rapid diagnostic test strip(RDT)and PCR examination.Results The patient did not visited malaria endemic areas,had history of massive blood transfusion in leukemia treatment,had chills,fever and was confirmed as falciparum malaria by microscopy with peripheral blood smears and RDT after blood transfusion.After tracing investigation,the blood donor was an overseas student from Africa,he had history of malaria before blood donation.His blood sample kept in blood bank was confirmed as P.falciparum positive by PCR examination.Conclusion The patient is a P.falciparum case infected by blood transfusion from a African student.

关 键 词： 恶性疟 输血 溯源调查

领　　域： []