作　　者： ;

机构地区： 南方医科大学

出　　处： 《临床医学研究与实践》 2020年第13期29-30,共2页

摘　　要： 目的探讨幽门螺杆菌(Hp)在慢性乙肝、乙肝肝硬化和乙肝肝硬化合并原发性肝癌中的感染率及与HBV-DNA的关系。方法选取我院2016年10月至2018年12月确诊的慢性乙肝患者168例为研究对象,其中乙肝组98例、肝硬化组46例、肝癌组24例,均行14C-尿素呼吸试验检测和HBV-DNA检测,分析HP感染率及与HBV-DNA的关系。结果168例患者中Hp感染率为68.45%;肝硬化组的Hp感染率高于乙肝组,肝癌组的Hp感染率高于肝硬化组(P<0.05)。Hp感染与HBV-DNA水平呈正相关(r=0.536,P=0.039)。结论Hp感染可能是乙肝并发肝硬化、肝癌的危险因素之一,乙肝患者接受根除Hp治疗可能会延缓疾病进展。 Objective To investigate the infection rates of Helicobacter pylori(Hp)in chronic hepatitis B,hepatitis B cirrhosis and hepatitis B cirrhosis with primary liver cancer and its relationship with HBV-DNA.Methods A total of 168 patients with chronic hepatitis B confirmed in our hospital from October 2016 to December 2018 were selected as the research objects,among which 98 patients in hepatitis B group,46 patients in cirrhosis group and 24 patients in liver cancer group,the patients were all tested with 14C urea breath test and HBV-DNA test,and the infection rate of Hp and its relationship with HBV-DNA were analyzed.Results In 168 patients,the Hp infection rate was 68.45%;the Hp infection rate in the liver cirrhosis group was higher than that in the hepatitis B group,and the HP infection rate in the liver cancer group was higher than that in the cirrhosis group(P<0.05).HP infection was positively correlated with HBV-DNA level(r=0.536,P=0.039).Conclusion Hp infection may be one of the risk factors for hepatitis B complicated with cirrhosis and liver cancer.Treatment of hepatitis B patients with Hp eradication may delay the progression of the disease.

关 键 词： 乙肝 幽门螺杆菌 原发性肝癌

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