作　　者： ; ; ; ;

机构地区： 深圳市妇幼保健院

出　　处： 《中国医药指南》 2019年第32期1-2,共2页

摘　　要： 目的采用牛奶相关症状评分(Cow’s Milk-related Symptom Score,CoMiSS)评估婴儿牛奶蛋白过敏治疗疗效。方法收集2015年6月至2017年6月在深圳市妇幼保健院儿科诊断为牛奶蛋白过敏的49例婴儿的临床资料,回避牛奶蛋白饮食4周,患儿治疗前后用CoMiSS对牛奶蛋白患儿症状进行评估。结果 CMPA患儿治疗前CoMiSS平均分为(8.95±3.14)分,治疗后4周平均分为(3.03±1.77)分。在哭闹方面,治疗前平均分为(2.03±1.56)分,4周后降至0;反流分数治疗前平均分为(2.16±1.40)分,治疗4周后降至(0.81±0.51)分;37例(75.51%)患者均出现程度不一的湿疹,治疗4周后均较前缓解;治疗前大便异常者(布里斯托1、2、6、7型)37例(75.51%),4周后大便性状好转(布里斯托3、4、5型)增至41例(83.67%);有呼吸道症状3例(6.12%),4周后降至1例(2.04%)。结论 CoMiSS能快速评估CMPA治疗疗效及客观地反映治疗前后症状演变的过程。 Objective To evaluate the efficacy of treatment for children with cow milk allergy by Cow’s Milk-related Symptom Score(CoMiSS). Methods From June 2015 to June 2017, 49 infants were diagnosed with cow milk protein allergy in the Department of Pediatrics of Shenzhen Maternal and Child Health Care Hospital. Diet elimination was performed in the 4 week.CoMiSS was used before and after treatment. Results The CoMiSS significantly decreased from(8.95±3.14) to(3.03±1.77) after 4 weeks treatment. The score of crying was from(2.03±1.56) to 0 after 4 weeks;the score of refluxing before treatment was(2.16±1.40), and decreased to(0.81±0.51);37 patients(75.51%)had eczema, then relieved after 4 weeks of treatment;37 cases(75.51%) of patients with abnormal stools before treatment(Bristol 1,2, 6, and 7), normal stool(Bristol 3, 4, 5) increased to 41 cases(83.67%)after 4 weeks of treatment;3 cases had respiratory symptoms(6.12%), decreased to 1 case after 4 weeks(2.04%). Conclusion CoMiSS can assess the efficacy of CMPA treatment quickly, and objectively reflect the process of symptom evolution before and after treatment.

关 键 词： 牛奶相关症状评分 牛奶蛋白过敏 治疗 评估

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