作　　者： ; ; ;

机构地区： 广州中医药大学第二临床医学院

出　　处： 《中华中医药杂志》 2017年第3期1059-1063,共5页

摘　　要： 目的:评价岭南传统天灸4号方治疗抑郁症失眠的临床疗效。方法:将符合纳入标准的90例抑郁症失眠受试者按1∶1∶1比例随机分为治疗组(岭南传统天灸4号方组,主要成分黄芥子粉、吴茱萸粉、郁金粉等)、对照1组(岭南传统天灸1号方组,主要成分为黄芥子粉、细辛、甘遂粉、廷胡索粉等)与对照2组(安慰剂组),每组30例。采用PHQ-9量表以及PSQI量表作为主要指标进行评测。结果:1治疗组与对照1组PHQ-9评分各时点与与治疗前比较差异均有统计学意义(P<0.05),3组治疗后的PSQI量表得分各时点与治疗前比较差异均有统计学意义(P<0.05)。23组患者PHQ-9量表评分各时点两两比较:治疗组、对照1组分别与对照2组比较,差异均有统计学意义(P<0.05)。33组患者PSQI量表各时点评分两两比较:疗程结束时,治疗组分别与对照1组及对照2组比较、对照1组与对照2组比较,差异有统计学意义(P<0.05);治疗组、对照1组分别与对照2组比较,差异均有统计学意义(P<0.05)。结论:岭南传统天灸4号方治疗抑郁症失眠是一种有效安全的方法。 Objective: To assess curative effect of Lingnan Tianjiu prescription 4 on the treatment of depression insomnia. Methods: the study was the random controlled method, and 90 patients conformed to the diagnostic criteria were allocated as a ratio of 1: 1: 1 into three groups: Lingnan traditional Tianjiu prescription 4(treatment group, yellowmustard, evodia rutaecarpa, radix curcumae,etc.), Lingnan traditional Tianjiu prescription No.1(control group 1, the prescription includes yellow mustard, herba asari cum radice,Euphorbia kansui,Rhizoma Corydalis,etc.), and placebo group(control group 2). Results: 1For PHQ-9 scores of Group 1 and Group 2, there was a significant difference(P<0.05) comparing before and after the intervention.For PSQI scores of 3 groups,there was a significant difference(P<0.05) comparing before and after the intervention. 2For PHQ-9 scores, Both treatment group and control group 1had significant differences comparing to control group 2(P<0.05). 3For PSQI scores, Both treatment group and control group 1had significant differences comparing to control group 2 at the end of treatment, and the same result as treatment group comparing to control group 1(P<0.05).At the following period, both treatment group and control group 1had significant differences comparing to control group 2(P<0.05). Conclusion: Analysis resultsof the trial indicated that Lingnan Tianjiu prescription 4 is safe and effective on depression insomnia.

关 键 词： 天灸 岭南传统天灸 号方 抑郁症失眠

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