作　　者： (）;

机构地区： 深圳市龙岗区妇幼保健院

出　　处： 《中国实用医药》 2019年第13期31-33,共3页

摘　　要： 目的探讨妊娠期糖尿病相关危险因素,为妊娠期糖尿病防控提供循证依据。方法 58例妊娠期糖尿病孕妇作为研究组,另选取同期60例正常孕妇作为对照组,分别就两组研究对象的年龄、孕产史、文化水平、年龄结构、腰臀比、体质量指数、25-羟基维生素D_3[25(OH)D_3]及糖尿病家族史等相关因素进行单因素分析,把单因素分析中有统计学意义的因素进行多因素Logistic回归分析。结果两组研究对象的年龄、孕产史、文化水平、年龄结构比较差异均无统计学意义(P>0.05)。研究组患者腰臀比及体质量指数分别为(0.98±0.05)、(29.9±2.6)kg/m^2,均明显高于对照组的(0.79±0.04)、(24.5±2.1)kg/m^2, 25(OH)D_3为(40.1±4.5)μg/L,明显低于对照组的(110.3±24.5)μg/L,糖尿病家族史比例84.5%明显高于对照组的0,差异均有统计学意义(P<0.05)。单因素分析显示,孕妇的腰臀比、体质量指数、25(OH)D_3及糖尿病家族史均为妊娠期糖尿病的相关影响因素(P<0.05)。多因素Logistic回归分析结果显示,孕妇体质量指数[OR=4.614, 95%CI=(1.815, 7.406), P=0.021<0.05]、腰臀比[OR=2.845,95%CI=(1.914, 9.686), P=0.042<0.05]、糖尿病家族史[OR=7.451, 95%CI=(2.875, 13.543), P=0.037<0.05]及25(OH)D_3[OR=3.314, 95%CI=(1.671, 7.146), P=0.043<0.05]均为妊娠期糖尿病的独立危险因素。结论孕妇体质量指数、腰臀比、糖尿病家族史及25(OH)D_3均为妊娠期糖尿病的独立危险因素,在临床工作中应对危险因素给予足够的重视,早诊断、早治疗,以获得理想的治疗效果。 Objective To discuss the risk factors of gestational diabetes mellitus and provide evidencebased basis for prevention and control of gestational diabetes mellitus.Methods There were 58 pregnant women with gestational diabetes mellitus as research group and 60 normal pregnant women in the same period as control group.The related factors of age,pregnancy and maternity history,educational level,age structure,waist-hip ratio,body mass index,25-hydroxyvitamin D3[25(OH)D3]and family history of diabetes mellitus in the two groups were analyzed by single factor analysis.Multivariate logistic regression analysis was performed for statistically significant factors in univariate analysis.Results There was no significant difference in age,maternity history,educational level and age structure between the two groups(P>0.05).The research group had obviously higher waist-hip ratio and body mass index respectively as(0.98±0.05)and(29.9±2.6)kg/m2 than(0.79±0.04)and(24.5±2.1)kg/m2 in the control group,obviously lower 25(OH)D3 as(40.1±4.5)μg/L than(110.3±24.5)μg/L in the control group,and obviously higher proportion of family history of diabetes as 84.5%than 0 in the control group.Their difference was statistically significant(P<0.05).Univariate analysis showed that waist-hip ratio,body mass index,25(OH)D3 and family history of diabetes mellitus in pregnant women were all related factors of gestational diabetes mellitus(P<0.05).Multivariate Logistic regression analysis showed that pregnant women’s body mass index[OR=4.614,95%CI=(1.815,7.406),P=0.021<0.05],waist-hip ratio[OR=2.845,95%CI=(1.914,9.686),P=0.042],family history of diabetes mellitus[OR=7.451,95%CI=(2.875,13.543),P=0.037<0.05]and 25(OH)D3[OR=3.314,95%CI=(1.671,7.146),P=0.043<0.05]were independent risk factors for gestational diabetes mellitus.Conclusion Pregnant women’s body mass index,waist-hip ratio,family history of diabetes mellitus and 25(OH)D3 are all independent risk factors of gestational diabetes mellitus.In clinical work,enough attention should be pai

关 键 词： 妊娠期糖尿病 体质量指数 腰臀比

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