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缺血预适应 缺血后适应对ST段抬高型心肌梗死患者的临床证据
Ischemic preconditioning/postconditioning in patients with ST-segment elevation myocardial infarction

作  者: ();

机构地区: 广东省人民医院

出  处: 《中国实用内科杂志》 2019年第9期789-791,共3页

摘  要: 再灌注治疗可以改善ST段抬高型心肌梗死患者的心肌缺血情况,但是由此引发的心肌缺血-再灌注损伤同样会影响患者预后。近年来,为预防和治疗心肌缺血-再灌注损伤,缺血预适应和缺血后适应等处理在动物实验中被证实有效,并已经被用于临床实践探索。文章旨在结合相关临床证据,对ST段抬高型心肌梗死患者中缺血适应研究进展进行综述,为急性心肌梗死的优化诊治提供理论依据。 Although myocardial ischemic condition can be improved by reperfusion therapy, the sequent myocardial ischemiareperfusion injury may associate with the adverse outcomes in patients with ST-segment elevation myocardial infarction. In the recent years, several therapies, such as ischemia preconditioning and ischemia postconditioning, have been proven effective in animal experiments and have been widely incorporated into clinical trials for the reduction of ischemia/reperfusion injury. Based on the previous clinical evidences, we review the study progress of ischemia conditioning in patients with ST-segment elevation myocardial infarction for optimizing the management of acute myocardial infarction.

关 键 词: 缺血预适应 缺血后适应 段抬高型心肌梗死

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