作　　者： (王月华）;

机构地区： 三河市燕郊人民医院心肾内科,河北三河065201

出　　处： 《系统医学》 2017年第5期33-35,102,共4页

摘　　要： 目的研究并探讨胺碘酮治疗急性心肌梗死合并心房颤动患者的临床疗效。方法选取2013年1月—2016年3月期间该院收治的80例急性心肌梗死合并心房颤动患者,采取单盲随机分组法随机分为两组,每组40例,对照组采用普罗帕酮治疗,观察组采用胺碘酮治疗,比较两组患者的临床总有效率、不良反应发生率、心室率、心功能指标、生活质量评分。结果观察组患者的临床总有效率为95.00%,相比于对照组患者的80.00%明显更高(P<0.05);观察组患者的不良反应发生率为10.00%,相比于对照组患者的27.50%明显更低(P<0.05);相比于治疗前,两组患者治疗后的心室率、NT-pro BNP均明显下降(P<0.05),其左室射血分数均明显增高(P<0.05),观察组患者治疗后的心室率、NT-pro BNP、左心射血分数相比于对照组差异有统计学意义(P<0.05);观察组患者的生活质量评分明显高于对照组(P<0.05)。结论采用胺碘酮治疗急性心肌梗死合并心房颤动具有显著的临床疗效,可有效改善心功能、生活质量,且安全性可靠。 Objective To research the clinical curative effect of amiodarone drugs in treatment of patients with acute myocardial infarction and auricular fibrillation. Methods 80 cases of patients with acute myocardial infarction and auricular fibrillation admitted and treated in our hospital from January 2013 to March 2016 were selected and randomly divided into two groups with 40 cases in each, the control group were treated with propafenone, while the observation group were treated with amiodarone drugs, and the total clinical effective rate, incidence rate of adverse reactions, ventricular rate, heart function index and quality of life score were compared between the two groups. Results The total clinical effective rate in the observation group was obviously higher than that in the control group （95.00% vs 80.00%）, （P〈0.05）, and the incidence rate of adverse reactions in the observation group was obviously lower than that in the con- trol group（10.00% vs 27.50%）（P〈0.05）, the ventricular rate and NT-proBNP after treatment in the two groups obviously decreased （P〈0.05）, and the left ventricular ejection fraction obviously increased, and all differences had statistical significance （P〈0.05）. Conclusion The clinical curative effect of amiodarone drugs in treatment of patients with acute myocardial infarction and auricular fibrillation is obvious, which can effectively improve the heart function and quality of life, and the safety is reliable.

关 键 词： 急性心肌梗死 心房颤动 胺碘酮