作　　者： (任虹）; (傅超美）; (何瑶）; (罗妮妮）; (季宁平）; (杨欢）;

机构地区： 成都中医药大学中药材标准化教育部重点实验室四川省中药资源系统研究与开发利用重点实验室-省部共建国家重点实验室培育基地,四川成都611137

出　　处： 《中药与临床》 2017年第1期18-22,共5页

摘　　要： 目的:通过对比分析大黄煮散颗粒与大黄饮片的指纹图谱,探讨两者之间质量是否存在差异。方法:采用HPLC指纹图谱,对大黄煮散颗粒与大黄饮片进行指纹图谱研究,并建立共有模式,采用"中药色谱指纹图谱相似度评价系统"对所得图谱进行相似度分析。结果:大黄煮散颗粒与大黄饮片的指纹图谱中,共有色谱峰有均有14个,相似度评价均大于0.9。结论:大黄煮散颗粒与大黄饮片的指纹图谱之间无明显差异,品质基本一致。 Objective： To explore whether there was a difference between the quality of Dahuang Zhusan Keli and Dahuang decoction pieces by comparative analysis of fingerprint. Method： HPLC chromatography was used to establish fingerprints of Dahuang Zhusan Keli and Dahuang decoction pieces. And similarity was analyzed using ＂traditional Chinese medicine chromatographic fingerprint evaluation system＂. Result： There were 14 common peaks in Dahuang Zhusan Keli and Dahuang decoction pieces with the similarity lager than 0.9. Conclusion： There is no significant difference between Dahuang Zhusan Keli and Dahuang decoction pieces which suggests that their qualities are basically the same.

关 键 词： 大黄 煮散颗粒 指纹图谱