作　　者： (孙琳）;

机构地区： 解放军第159中心医院血液科,河南驻马店463000

出　　处： 《临床医学》 2017年第7期32-34,共3页

摘　　要： 目的探讨缺铁性贫血(IDA)和慢性病贫血(ACD)骨髓涂片及骨髓活检的临床效果。方法选取2012年1月至2015年12月56例IDA患者和64例ACD患者作为研究对象,根据病情分为IDA组和ACD组,均行骨髓涂片及骨髓活检检查。比较两组患者的骨髓增生程度、骨髓铁染色比例和骨髓活检Gomori网状纤维染色分级比例。结果在骨髓涂片检查中,ACD组骨髓增生程度、粒红比值明显高于IDA组(P<0.05);ACD组细胞外铁阳性分布明显高于IDA组(P<0.05);两组患者细胞内铁数目比较差异未见统计学意义(P>0.05);ACD组网状纤维增生程度明显高于IDA组(P<0.05)。结论在IDA与ACD的鉴别诊断中骨髓活检有一定临床意义,骨髓活检联合骨髓涂片检查有助于提高ACD的诊断水平。 Objective To investigate the clinical effect of bone marrow smear and bone marrow biopsy on patients with iron-deficiency anemia（IDA） and anemia of chronic disease（CDA）. Methods From January 2012 and December 2015, 56 patients with IDA and 64 patients with ACD were selected as study subjects, according to the condition, they were divided into IDA group and ACD group, the patients were performed with bone marrow smear and bone marrow biopsy. The degree of bone marrow proliferation, bone marrow iron staining ratio and bone marrow biopsy Gomori reticular fiber staining were compared between the two group. Results In the examination of bone marrow smear, the ratio of bone marrow hyperplasia in ACD group was significantly higher than that in IDA group （ P 〈 0. 05 ） ; the distribution of extracellular iron in ACD group was significantly higher than that in IDA group（P 〈 0. 05）. There was no significant difference in the number of iron in the cells between the two groups （P 〉 0.05） ; the degree of reticular fiber proliferation in ACD group was significantly higher than that in IDA group （P 〈 0. 05 ）. Conclusion Bone marrow biopsy combined with bone marrow smear examination is helpful to improve the diagnostic level of ACD in the diagnosis of bone marrow biopsy in IDA and ACD.

关 键 词： 缺铁性贫血 慢性病贫血 骨髓涂片 骨髓活检 临床效果