作　　者： (杨军）; (杨群）;

机构地区： 大连医科大学附属第一医院脊柱外科,辽宁大连116011

出　　处： 《大连医科大学学报》 2017年第4期397-402,共6页

摘　　要： 因外伤、肿瘤、感染等原因造成的骨缺损是骨科临床常见疾患,目前解决这一问题的主要方法为自体骨移植或同种异体骨移植。自体骨移植主要存在取骨量有限,造成附加损伤,感染,出血等缺陷。同种异体骨存在价格昂贵,免疫排斥反应等问题。此外,多种骨材料替代物也越来越多地应用于研究和临床,比如羟基磷灰石,生物陶瓷等。近年来,多孔金属材料由于其良好的生物相容性,较好的抗压强度和与骨接近的弹性模量等优点逐渐成为研究热点。本文针对多孔镁、多孔铁、多孔镍、多孔钽、多孔钛等不同材质的多孔金属材料,对其构建方法、理化特性、基础研究、临床应用等方面进行综述。 Bone defect caused by trauma, tumor and infection is a common disease in orthopedics. Autogenous and allograft bone graft is mainly limited by the amount of graft bone, additional damage, infection, bleeding, immune rejection, etc. A variety of bone substitutes have also been increasingly used in clinical research, such as hydroxyapatite and bioceramics. In recent years, porous metal materials have gradually become the focus of research because of their good biocompatibility, good compressive strength and similar elastic modulus with bone. In this paper, we reviewed the construction methods, physicochemical properties, basic research and clinical application of porous metal materials such as porous magnesium, porous iron, porous nickel, porous tantalum and porous titanium.

关 键 词： 骨缺损 植入材料 多孔金属