作　　者： (宋勇）; (秦高平）; (杜立学）; (胡海田）; (张昊宇）;

机构地区： 陕西省人民医院·西安交通大学第三附属医院肝胆外科,陕西西安710068

出　　处： 《西部医学》 2017年第9期1217-1220,共4页

摘　　要： 目的分析SIS镁合金可吸收胆管支架治疗恶性梗阻性黄疸的临床疗效。方法选取67例接受胆道金属支架引流术(EBMSD)的恶性梗阻性黄疸患者,按照置入不同金属支架分为对照组和实验组,对照组患者置入普通镍钛合金支架,实验组患者置入SIS镁合金可吸收支架。检测两组患者术前1周及术后1周血清总胆红素(TBIL)、丙氨酸转氨酶(ALT)、碱性磷酸酶(ALP)、天门冬氨酸氨基转移酶(AST)、直接胆红素(DBIL)和间接胆红素(IBIL),观察两组患者术后并发症情况及两组患者6个月生存率和引流通畅率。结果对照组插管成功率为91.7%,实验组患者插管成功率为93.5%,两组对比无明显差异(P>0.05);两组患者术后1周肝功能指标(TBIL,ALT,ALP,AST,DBIL,IBIL)明显优于术前1周(P<0.05),但两组之间术后1周肝功能指标对比无明显差异(P>0.05);实验组患者术后并发症明显低于对照组患者(P<0.05);实验组患者6个月生存率为82.3%,引流通畅率为72.4%,明显优于对照组患者的66.7%和39.4%(P<0.05)。结论 SIS镁合金可吸收胆管支架能有效缓解患者恶性梗阻性黄疸症状,改善肝功能,延长患者生存期;术后并发症低于普通镍钛合金支架。 Objective To investigate the clinical effect of SIS magnesium alloy absorbable biliary stent in the treatment of patients with malignant obstructive jaundice. Methods 67 patients with malignant obstructive jaundice treated with EBMSD in our hospital were selected and divided into control group and observation group according to the different metal biliary stent. The patients in control group accepted normal Nickel titanium alloy stent while the patients in observation group accepted magnesium alloy absorbable biliary stent. The TBIL, ALT, ALP, AST, DBIL, IBIL of all the patients were detected before and after one week of the operation. The complication after operation, survival rate and drainage unobstructed rate after 6 months were observed. Results The stents placing successful rate of control group was 917% and 93.5% for observation group （P〉0.05）. After operation, TBIL, ALT, ALP, AST, DBIL, IBIL of the two groups were better than those before operation and there was no significant difference between the two groups （P〉0.05）. On the other hand, more complications was observed in the control groups （P〈0.05）. After 6 months, the survival rate of observation group was 82.3% and drainage unobstructed rate was 72.4, which were better than those in control group （P〈0.05）. Conclusion SIS magnesium alloy absorbable biliary stent could improve the liver function and reduce the malignant obstructive jaundice symptoms and longer the life of the patients with malignant obstructive jaundice.

关 键 词： 镁合金 可吸收 胆管支架 恶性梗阻性黄疸