作　　者： (王学林）; (李榆庆）; (安燕萍）; (姚菊仙）; (毛淑贞）;

机构地区： 昆明农药有限公司,昆明650401

出　　处： 《农药》 2017年第8期573-576,共4页

摘　　要： [目的]筛选和优化28%苄嘧磺隆·扑草净泡腾颗粒剂配方。[方法]采用挤压造粒制造工艺,通过实验对泡腾崩解剂、润湿分散剂、黏结剂、润滑剂、吸湿剂等助剂和填料进行筛选和优化。[结果]实验得最优配方:苄嘧磺隆2.5%,扑草净25.5%,柠檬酸20%,碳酸氢钠24%,润湿分散剂KNY-PB5%,膨润土2.5%,滑石粉1%,硬脂酸镁1%,吸湿剂A 7%,凸凹棒土和高岭土(按质量比2∶3)补足至100%。[结论]用该配方配制的样品具有良好的漂浮和自分散性能,各项指标符合泡腾颗粒剂的要求,产品质量稳定。 [Aims] The formulation of bensulfuron-methyl · prometryn 28% effervescent granule was screened and optimized. [Methods] The extrusion granulation process was used to screen and optimize the auxiliary such as effervescent disintegrating agent, wetting dispersing agent, adhesive, lubricant, hygroscopic agent and filler selection.[Results] The optimal experimental formula was： bensulfuron-methyl 2.5%, prometryn 25.5%, citric acid 20%, sodium bicarbonate 24%, wetting dispersing agent KNY-PB 5%, bentonite 2.5%, talc 1%, magnesium stearate 1%, hygroscopic agent A 7%, the mixture of attapulgite clay and kaolin（2∶3, by mass） adds to 100%. [Conclusions] The sample has good floating and self-dispersion performance, each indexes of the effervescent granule meets with the requirements,and the product quality is stable.

关 键 词： 苄嘧磺隆 扑草净 泡腾颗粒剂 配方研制