作　　者： (陈金华）; (苌新明）;

机构地区： 西安交通大学医学部,陕西西安710061 西北工业大学医院,陕西西安710072

出　　处： 《临床医学研究与实践》 2017年第26期30-31,共2页

摘　　要： 目的观察慢性胃肠功能紊乱应用曲美布汀、多塞平、培菲康联合治疗的效果。方法随机将在本院治疗的104例慢性胃肠功能紊乱患者分为研究组和对照组,每组52例,研究组给予曲美布汀、多塞平、培菲康联合治疗,对照组给予谷维素、多塞平、培菲康联合治疗,观察两组患者的临床治疗效果、临床症状消失时间及不良反应发生情况。结果研究组的治疗总有效率(96.2%)高于对照组(82.7%)(P<0.05);研究组上腹痛、腹胀、早饱、嗳气、恶心等症状消失时间均短于对照组(P<0.05);两组患者不良反应发生率比较,差异不显著(P>0.05)。结论慢性胃肠功能紊乱应用曲美布汀、多塞平、培菲康联合治疗时,效果良好,不良反应少。 Objective To observe the effect of trimebutine combined with doxepin and bifico in the treatment of chronic gastrointestinal disorders. Methods One hundred and four patients with chronic gastrointestinal disorders were randomly divided into study group and control group, with 52 cases in each group. The study group was given trimebutine combined with doxepin and bifico treatment, and the control group was given oryzanol combined with doxepin and bifieo treatment. The clinical effect, disappearance time of clinical symptoms and adverse reactions were observed in the two groups. Results The total effective rate of the study group （96.2%） was higher than that of the control group （82.7%） （P〈0.05）. The disappearance times of clinical symptoms such as abdominal pain, abdominal distension, early satiety, belching, nausea in the study group were shorter than those in the control group （P〈0.05）. There was no significant difference between the two groups in the incidence rate of adverse reactions （P〉0.05）. Conclusion The trimebutine, doxepin and bifico has a good therapeutic effect and few adverse reactions chronic gastrointestinal disorders .

关 键 词： 曲美布汀 多塞平 培菲康 慢性胃肠功能紊乱