作 者: (张小玲); (王秋鼓); (姚血明); (宁乔怡); (周静); (黄颖); (马武开);
机构地区: 贵阳中医学院第二附属医院风湿免疫科,贵州贵阳550003
出 处: 《贵阳中医学院学报》 2017年第5期91-94,共4页
摘 要: 类风湿关节炎(RA)的发病机制目前仍不清楚,其发病涉及复杂的免疫机制,多种免疫细胞、细胞因子。近年来研究发现白介素-17(IL-17)在RA患者中异常升高,与RA的滑膜炎症、软骨和骨的破坏有关。本文对近年来IL-17在RA发病机制中的作用进行综述。 The pathogenesis of Rheumatoid Arthritis (RA) is still uncertain for the pathogenesis of RA involves complex immune mechanisms, a variety of immune cells and cytokines. In recent years, studies have showed that interleukin-17 (IL-17) elevated abnormally in RA patients, which is related to RA synovial in- flammation, cartilage and bone destruction. This review summarizes the function of IL-17 in the pathogenesis of RA in recent years.