作　　者： (励晶）; (李成江）; (王黎明）; (陈奋）; (夏东霞）; (陈曦）;

机构地区： 宁波大学医学院附属医院内分泌代谢科,315020

出　　处： 《浙江临床医学》 2017年第10期1905-1907,共3页

摘　　要： 目的比较三餐后步行和每日单次步行模式对2型糖尿病（T2DM）患者的餐后血糖疗效及安全性。方法将122例稳定使用甘精胰岛素＋阿卡波糖及二甲双胍片治疗的长病程T2DM患者，随机分为每日单次步行组（45min）和每日三餐后步行组（三餐后各15min），两组均为中等运动强度且总运动时间一致。16周后比较两组患者的空腹血糖（FBG）、3餐后2h-＆糖（2hPG）、糖化血红蛋白（HbA1C）、体重指数（BMI）、日胰岛素剂量、低血糖事件及患者满意度。结果治疗后两组患者的FBG、HbA1C、BMI、日胰岛素剂量和低血糖事件无明显差异（P均〉0．05）；每日三餐后步行组的三餐2hPG均低于每日单次步行组（P均〈0．05），两组患者的治疗满意度均提高，但每日三餐后步行组对治疗的方便灵活性满意度及总体满意度均高于每日单次步行组（P〈0．05）。结论每日三餐后步行模式较单次步行模式更能改善长病程T，DM患者的三餐后2hPG，且前者对长期静坐的患者在治疗上更方便和灵活，有利于长期坚持。 Objective To compare the effect and safety of the standard 45 min and post-meal walking regimens in Type 2 diabetes mellitus long course of disease with 2-hour postprandial blood glucose. Methods 122 type 2 diabetic patients who were in long course of disease and in treatment of long duration of insulin glargine, acarbose and metformin were randomly divided into single walking group （ single 45 min ） and post-meal walking group （ 15rain after 3 meals ） .The two sets were of moderate exercise intensity, and the total walking time was equal.After 16 weeks, fasting blood glucose （ FBG ） , 2 hour postprandial blood glucose （ 2hPG ） , glycosylated hemoglobin （ HbIAC ） , body mass index （ BM[ ） , daily insulin dose, risk of hypoglycemia, patient satisfaction were compared between the two sets of patients. Results There were no significant difference in fasting blood glucose, glycosylated hemoglobin, hypoglycemia, BMI, daily insulin dose and incidence of hypoglycemia in the two sets （ P〉0.05 ） .Overall 2hPG of post-meal walking group were lower than that of single 45min walking group （ P〈0.05 ） .Two groups of patients＇ treatment satisfactions were improved （ P〈0.05 ） .The convenience, flexibility and overall satisfaction of the post^meal walking group were higher than that of the single walking group （ P〈0.05 ） . Conclusion In sedentary type 2 diabetes mellitus of long course of disease, a prescription to walk daily after 3 meals for 15min/time is associated with improvements in postprandial glycaemia when compared with advice to walk for 45 min/day in a single bout at an unspecified time.To sedentary type 2 diabetes mellitus, post- meal walking pattern is more convenient and flexible, and is favor to long-term persistence.

关 键 词： 单次步行 餐后步行 餐后 血糖 型糖尿病