作　　者： (冯静娟）; (向锋）; (程健）; (苟晔荔）;

机构地区： 四川省医学科学院·四川省人民医院肛肠科,四川成都610072

出　　处： 《实用医院临床杂志》 2017年第5期113-115,共3页

摘　　要： 目的探讨脱细胞异体真皮基质填塞在治疗肛瘘中的临床疗效。方法 2013年12月至2015年12月我院收治的64例肛瘘患者,根据不同治疗方法分为治疗组(脱细胞异体真皮基质填塞术)和对照组(肛瘘切开术或切开挂线术)各32例。比较两组术后疼痛评分、肛门失禁评分、愈合时间、复发率和治愈率情况。结果治疗组在术后疼痛时间评分、肛门失禁评分、愈合时间、肛门畸形方面比较,治疗组优于对照组,差异有统计学意义P<0.01);两组治愈率和复发率比较,差异无统计学意义(P>0.05)。结论脱细胞异体真皮基质填塞治疗肛瘘术后疼痛轻、创伤小、创面愈合时间短,较好保护了肛门功能。 Objective To explore the clinical effect of acellular extracellular matrix （AEM） in the treatment of anal fistula. Methods A retrospective analysis of clinical data of 64 patients with anal fistula from December 2013 to December 2015 in our hospi- tal was collected. The patients were allocated into the treatment group （ undergoing AEM） and control group （ undergoing fistulotomy or incision-thread-drawing procedure） ,32 patients in every groups. Pain scores, anal incontinence scores, wound healing time, recurrence rate and cure rate were compared between the two groups. Results There was no statistic difference in recurrence rate and cure rate between the two groups （ P 〉 0.05 ）. The difference was statistically significant in the postoperative pain scores, anal incontinence scores ,wound healing time and anal deformity between the two groups with superiority of the treatment group over the control group （P 〈 0. 05）. Conclusion AEM in the treatment of anal fistula has the advantages of less pain,less trauma, shorter wound healing time and better anal control ability.

关 键 词： 脱细胞异体真皮基质 肛瘘 临床疗效