作　　者： (陈振）; (刘朝）; (李冬冬）; (徐浩文）; (郭新宾）; (管生）;

机构地区： 郑州大学第一附属医院神经介入科,450052

出　　处： 《介入放射学杂志》 2017年第9期775-778,共4页

摘　　要： 目的评价低剖面编织型设计的自膨式LVIS支架辅助弹簧圈栓塞治疗颅内动脉瘤的安全性及有效性。方法回顾性分析2014年4月至2016年6月收治的127例LVIS支架辅助弹簧圈栓塞治疗颅内动脉瘤患者临床资料,分析手术安全性、术后即刻效果、复发率及临床、影像学随访结果。结果127例颅内动脉瘤患者介入栓塞术中成功植入130枚LVIS支架,1例植入失败,技术成功率99.2%。7例术中或术后出现支架内血栓事件(7/127,5.5%),无围手术期出血、死亡。术后即刻动脉瘤完全闭塞112枚(88.1%),瘤颈残余15枚(11.9%)。术后平均随访8个月,37例影像学复查显示33例(89.1%)动脉瘤完全闭塞,4例(10.9%)瘤体仍显影,其中3例为术后即刻有瘤体显影,1例为动脉瘤复发,无死亡。结论LVIS支架辅助栓塞颅内动脉瘤安全有效,但远期疗效有待进一步随访观察。 Objective To evaluate the clinical safety and efficacy of LVIS stent （a low profile knitting designed self-expandable stent） in assisting endovascular embolization for intracranial saccular aneurysms. Methods A total of 127 patients with intracranial saccular aneurysm, who were admitted to authors＇ hospital during the period from April 2014 to June 2016 to receive LVIS stent-assisted endovascular embolization, were retrospectively analyzed. The safety of the operation, the immediate postoperative outcomes, the recurrence rate, and the clinical and radiographic follow-up results were analyzed. Results A total of 130 LVIS stents were successfully implanted in the 127 patients with intracranial saccular aneurysm, implantation failure was seen in one patient, the technical success rate was 99.2%. During or after the endovascular embolization process in-stent thrombosis was observed in 7 patients （7/127, 5.5%）. Neither perioperative bleeding nor death occurred. Immediately after the operation, complete occlusion of the aneurysm was obtained in 112 aneurysms （88.1%） and neck remnant was observed in 15 aneurysms （11.9%）. The patients were followed up for a mean period of 8 months. Follow-up angiography was performed in 37 patients, which showed that complete occlusion of the aneurysm was obtained in 33 patients （89.1%）, and visualization of the aneurysm was seen in 4 patients （10.9%）, including 3 patients who had aneurysm visualization immediately after embolization and one patient who had aneurysm recurrence. No death occurred. Conclusion The use of LVIS stent to assist endovascular embolization for intracranial saccular aneurysms is safe and effective, although its long-term effect needs further observation. （J Intervent Radiol, 2017, 26： 775-778）

关 键 词： 颅内动脉瘤 支架 血管内介入治疗