作　　者： (傅璟）; (李雪姣）; (朱慧莉）; (宋永）; (杨诗源）; (谭婧）; (周国君）; (黄薇）;

机构地区： 四川大学华西第二医院妇产科,成都610041 出生缺陷与相关妇儿疾病教育部重点实验室（四川大学）,成都610041

出　　处： 《四川大学学报（医学版）》 2017年第5期736-739,共4页

摘　　要： 目的分析2008年汶川大地震后地震重灾区高龄妇女再次妊娠结局,为高龄妇女的孕前保健提供参考。方法回顾性调查接受地震重灾区再生育全程服务的542例妊娠经产妇的临床资料,根据妊娠终止年龄分为高龄组(≥35岁)和非高龄组(<35岁),比较两组妊娠结局,包括基本情况、妊娠率、妊娠合并症/并发症、妊娠结果及围产儿情况。结果 2008~2013年542例再生育妇女(高龄组366例,非高龄组176例)共妊娠622人次,生育(足月和早产)517人次,活产522人(双胎6例),有出生缺陷3例。高龄组的两年内累积妊娠率低于非高龄组,高龄组妊娠高血压疾病、妊娠期糖尿病、多胎、胎儿宫内窘迫、低出生体重儿、出生缺陷的发生率较高,非高龄组足月活产率较高、流产率较低,但差异无统计学意义。结论接受地震灾区再生育全程服务的高龄经产妇再次妊娠结局与非高龄经产妇相当。 Objective To evaluate pregnancy outcomes of multiparae in women with advanced age （≥35 yr. ） after the 2008 Wenchuan earthquake. Methods Clinical data of 542 pregnant women with prenatal care in Wenchuan during 2008-2013 were reviewed, comparing pre-conception conditions, pregnant rates, pregnant complications, and perinatal outcomes between those younger （n= 176） and older （n= 366） than 35 years. Results In the 542 women, 622 conceptions were reported, with 517 deliveries and 522 live births. The women with advanced age had lower cumulative pregnancy rate （two-year）, higher incidence of hypertensive disorders of pregnancy, gestational diabetes, multiple pregnancy, fetal distress, low birth weight and birth defects than their younger counterparts. The younger women also had higher term live birth rate and lower miscarriage rate. But the differences showed no statistical significance. Conclusion Prenatal care brings similar pregnant outcomes to multiparae in women with advance aged and ,-ounger aged.

关 键 词： 高龄经产妇 再次生育 活产 流产