作　　者： (周薇）; (张志将）; (王丽君）; (刘晓雪）; (宇传华）;

机构地区： 武汉大学健康学院流行病与卫生统计学系,湖北武汉430071

出　　处： 《中国癌症杂志》 2017年第8期634-640,共7页

摘　　要： 背景与目的:子宫颈癌是女性生殖系统最常见的恶性肿瘤之一,严重威胁着女性的健康。密切掌握中国女性子宫颈癌死亡现况及近30年间的变化趋势,为子宫颈癌的防控策略提供科学依据。方法:汇总1987—2014年中国女性子宫颈癌死亡率数据,描述年龄标化率和截缩率的特征及趋势,利用Joinpoint回归模型估计子宫颈癌死亡率的变化趋势。结果:1987—2014年,农村女性子宫颈癌死亡率整体高于城市,城市及农村年均变化均呈现下降趋势,且农村平均下降速度显著快于城市,城市平均每年下降1.79%(P<0.01),农村平均每年下降3.94%(P<0.01)。城乡差距逐渐减小,2010年之后城市截缩率超过农村。城市30~54岁女性子宫颈癌死亡率随年份上升,城市高龄女性及农村30~54岁女性随年份下降。结论:1987—2014年,中国女性子宫颈癌死亡情况整体好转,但城市中青年人群持续上升,城乡高龄人群在近10年也出现明显的上升趋势。 Background and purpose： Cervical cancer is one of the most common malignant tumors and poses a great threat to women’s fitness. Monitoring its present status and variations over the past 3 decades could provide scientifc basis for prevention and control strategies of cervical cancer in China. Methods： This study collected the mortality rates of cervical cancer data in Chinese women from 1987 to 2014, described the features and trends of age-standardized rates and truncated rates, and estimated the variations via joinpoint regression models. Results： The mortality rates of cervical cancer for rural women were roughly higher than those for urban women. It showed downward trends for both urban and rural women, and the average rate of decrease for rural women （AAPC=3.94%, P〈0.01） was higher than that for urban women （AAPC=1.79%, P〈0.01）. The gap between urban and rural areas was narrowing, with urban rates exceeding rural rates after 2010. The mortality rates of cervical cancer increased with time for urban women aged from 30 to 54, decreased with time for the elderly urban women and all the rural women. Conclusion： The overall mortality rates of cervical cancer took a desirable turn in China over the past 3 decades, while the status for the middle-aged urban women was getting worse as well as the elderly in both urban and rural areas during the past 10 years.

关 键 词： 子宫颈癌 死亡率 回归 趋势