作 者: (田永奇); (林圣楠); (周洪); (刘永宏);
机构地区: 福州大学生物科学与工程学院,福州350108 中国科学院南海海洋研究所,中国科学院热带海洋生物资源与生态重点实验室,广州510301
出 处: 《天然产物研究与开发》 2017年第9期1512-1516,1528,共6页
摘 要: 利用硅胶柱色谱、凝胶柱、反向柱色谱和高效液相等手段对深海来源的真菌Aspergillus sp.SCSIO Ind09 F01的代谢产物进行分离纯化,从中分离得到了13个化合物。通过理化性质、波谱分析方法结合文献对照,鉴定了化合物的结构分别为:sydowinin B(1)、pinselin(2)、1,6-dihydroxy-3-methyl-8-carbom ethoxyxanthone(3)、MT-1(4)、1-hydroxy-6,8-dimethoxy-3-methyl-9,10-anthraquin one(5)、methyl orsellinate(6)、orcinol(7)、mrlactone1(8)、Janthinone(9)、cyclo-(L-trptophyl-L-phenylalanyl)(10)、13-O-acetylsydowinin B(11)、7-Hydroxy-2,5-dimethylchromone(12)、Acremolin(13)。 To study the chemical constituents from the deep-sea fungus Aspergillus sp. S CSIO Ind09F01. Thirteen c o m -pounds were isolated from the EtOAc extract using silica gel,Sephadex LH-20,ODS and HPLC methods. Based on the spectroscopic analysis,their structures were identified as sydowinin B (1) ,pinselin(2) , 1,6-dihydroxy-3-methyl-8-car- bom ethoxyxanthone(3) , MT-1 (4) , 1-hydroxy-6,8-dimethoxy-3-methyl-9,10-anthraquin one (5) , methyl orsellinate (6 ) ,orcinol( 7) , mrlactonel ( 8 ) , Janthinone ( 9 ) , cyclo-( L-trptophyl-L-phenylalanyl) (10) , 13-O-acetylsydowinin B (11) ,7-Hydroxy-2,5-dimethylchromone (12) ,Acremolin(13).