作　　者： (肖华蓉）;

机构地区： 广元市妇幼保健计划生育服务中心,四川广元628000

出　　处： 《中国计划生育和妇产科》 2017年第9期32-35,共4页

摘　　要： 目的分析血小板减少对妊娠结局的影响。方法选取2014~2016年广元市妇幼保健计划生育服务中心收治的妊娠合并特发性血小板减少性紫癜(idiopathic thrombocytopenic purpura,ITP)患者60例作为观察组,同时选取60例妊娠期血小板减少症(gestational thrombocytopenia,GT)患者作为对照组,根据血小板计数(platelet count,PLT)将60例ITP孕妇分为3组,甲组PLT≤20×10~9/L,乙组(20~50)×10~9/L,丙组≥50×10~9/L,观察3组ITP孕妇的妊娠结局。结果孕期首次PLT减少发生在孕24周内和PLT首次减少<50×10~9/L是ITP独立预测指标;3组孕妇剖宫产率、自然分娩率比较,差异有统计学意义(P<0.05);3组产妇产后出血率、早产、胎儿窘迫、新生儿窒息发生率比较,差异无统计学意义(P>0.05)。结论血小板首次减少发生时间及减少计数可早期诊断妊娠合并ITP,但对围生儿结局无不良影响。 Objective To study the effect of thrombocytopenia on pregnancy outcomes. Methods 60 patients with idiopathic thromboeytopenic purpura（ITP） from January 2015 to December 2015 in Guangyuan Maternal and Child Health Care Family Planning Service Center were selected as the observation group, and 60 patients with gestational thrombocytopenia （GT） were selected as the control group. Retrospectively analyzed the clinical data. 60 cases of ITP pregnant women were divided into three groups according to the platelet count： group A PLT≤20 × 10 9/L, group B （20 -50） × 10 9/L, group C 〉150 × 10 9/L. Observed the pregnancy outcomes of three groups of ITP pregnant women. Results The first PC reduction during pregnancy occurred within 24 weeks of pregnancy and the first reduction in PC count 〈 50 × 10 9/ L was the ITP independent predictor. The cesarean section rate and natural delivery rate of the three groups were statistically significant（P 〈0. 05 ）. There were no significant differences in the incidence of postpartum hemorrhage, preterm birth, fetal distress and neonatal asphyxia in the three groups （P 〉 0. 05 ）. Conclusion The occurrence of time and count of first reduction in platelet can be early diagnosis of pregnancy associated with ITP,but has no adverse effects on perinatal outcomes.

关 键 词： 特发性血小板减少性紫癜 妊娠期血小板减少症 诊断 妊娠结局