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电针和圆利针治疗制动致膝关节功能障碍兔模型的治疗效果
Comparison Research of EA and RSA Treating Knee Joint Dysfunction Caused by Knees Immobilization in Rabbit Models

作  者: (陈紫岳); (黄怡然); (李娜); (夏晶); (马莹); (张冰月); (梁亚峰); (李文迅);

机构地区: 北京中医药大学针灸推拿学院,北京100020

出  处: 《世界中医药》 2017年第8期1927-1932,共6页

摘  要: 目的:比较电针和圆利针治疗制动致膝关节功能障碍模型兔的疗效及机制。方法:将新西兰兔24只随机分为4组:正常组、模型组、圆利针组和电针组,每组6只,除正常组外均建立制动致膝关节功能障碍模型。造模6周后干预组接受干预。于造模后4,8,12周测量兔患侧Lequesne MG总指数;于造模后13周通过光学显微镜观察股直肌超微结构;于造模第12周通过X线对膝关节进行整体评价。结果:行为学:电针与圆利针对于关节功能障碍、局部反应、肿胀有明显的疗效(P<0.05)且2种方法差异无统计学意义(P>0.05);光镜:电针组(P<0.05)与圆利针组(P<0.01)治疗起效明显但圆利针组疗效更佳;X线:干预组结果明显优于模型组且圆利针组较佳。结论:针和圆利针对于固定制动引起的关节功能障碍均有确切疗效,但圆利针通过对受损软组织的直接干预,能更有效地治疗制动引起的关节功能障碍。 Objective: To compare curative effect and mechanism of EA therapy and RSA therapy in treating knee joint dysfunction caused by knees immobilization. Methods: Randomly divided 24 New Zealand rabbits into four groups: normal group,model group,RSA group and EA group,with 6 rabbits of each group. Make knee joint dysfunction model except for normal group. Treatment groups received treatment after 6 weeks of modeling. The Lequesne MG was evaluated at 4,8,12 weeks after modeling. HE staining was observed at 13 weeks after modeling. X-ray were used to assess the radiological changes of knee joint dysfunction model rabbits. Results: Behavioral: EA and RSA therapy can effectively relieve movement disorder( P 0. 05),swelling local reaction in knee joint dysfunction model rabbits and the effects were similar within two groups( P 0. 05. Light microscope: EA( P 0. 05) and RAS( P 0. 01) therapies could all worked effectively but RSA group behaves better than EA group. X-ray: Tow therapies could all worked effectively but RSA group is superior to EA group. Conclusion: EA and RSA therapy showed definite effect on knee joint dysfunction model rabbits caused by knees immobilization,and RSA therapy is better for its direct intervention on soft tissue.

关 键 词: 电针 圆利针 行为学 超微结构 线

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