作　　者： (姜嫄嫄）; (赵文景）; (夏军）;

机构地区： 首都医科大学附属北京中医医院,北京100010

出　　处： 《世界中医药》 2017年第8期1781-1785,共5页

摘　　要： 目的:观察益气养阴活血方治疗气阴两虚血瘀型2型糖尿病肾病早期患者的临床疗效。方法:选取首都医科大学附属北京中医医院收治的2型糖尿病肾病早期患者60例,随机分为观察组和对照组,观察益气养阴活血方对气阴两虚血瘀型2型糖尿病肾病早期患者血糖、尿微量白蛋白(Micro Albumin,mALB)、尿微量白蛋白/尿肌酐(Micro Albumin/Urinecreatinine,mALB/Ucr)及临床症状的影响,并与对照组进行对比研究。结果:治疗后2组的mALB、mALB/Ucr较治疗前比较显著下降,差异有统计学意义(P<0.05),且治疗后2组的mALB、mALB/Ucr比较,差异有统计学意义(P<0.05),益气养阴活血方治疗后血糖均有显著下降,差异有统计学意义(P<0.05),临床症状有所改善。结论:益气养阴活血方可降低患者微量蛋白尿及尿微量白蛋白/尿肌酐比值,并可降低血糖、改善临床症状,对治疗2型糖尿病肾病有积极意义。 Objective： To observe the clinical efficacy of Yiqi Yangyin Huoxue Decoction in treating qi and yin deficiency and blood stasis in patients with early stage-type 2 diabetic nephropathy. Methods： A total of 60 patients with early stage-type 2 diabetic nephropathy were randomly divided into two groups： treatment group and control group. Observe the effect of Yiqi Yangyin Huoxue decoction on blood glucose,mALB,mALB/Ucr and clinical symptoms in patients with qi and yin deficiency and blood stasis of early stage-type 2 diabetic nephropathy. Comparison with the control group was made. Results： After treatment,mALB and mALB/Ucr in the two groups were significantly decreased（ P 0. 05）; and the two groups were significantly different in terms of mALB/Ucr and mALB（ P 0. 05）,with the blood glucose significantly decreased in the treatment group（ P 0. 05）. The Clinical symptoms were improved. Conclusion： There is positive significance in Yiqi Yangyin Huoxue decoction in the treatment of early stage-type 2 diabetic nephropathy by reducing mALB,mALB/Ucr,and blood sugar,thereby improving the clinical symptoms.

关 键 词： 益气养阴活血方 气阴两虚血瘀型 糖尿病肾病早期 微量白蛋白