作　　者： (王晓庆）; (贺京军）; (黄红艳）;

机构地区： 广东省第二人民医院体检科,广东广州510317

出　　处： 《医学临床研究》 2017年第8期1468-1471,1474,共5页

摘　　要： 【目的】探讨超声弹性成像（UE）联合微钙化增强技术在良恶性乳腺结节中的鉴别价值。【方法】回顾性分析2013年3月至2016年2月在本院接受超声检查的乳腺肿块患者80例（95个结节）的临床资料，所有患者均完成二维超声、UE及超声萤火虫微钙化增强扫描，以病理结果作为对照，分析UE联合微钙化增强技术鉴别乳腺良恶性结节的临床价值。【结果】二维超声鉴别良恶性乳腺结节敏感度为85．19％（46／54），特异度为65．85％（27／41），准确率为76．84％（73／95）；超声萤火虫微钙化增强技术诊断敏感度85．71％（54／68），特异度77．78％（21／27），准确率为78．95％（75／95）；UEItoh5分法鉴别诊断敏感度为88．14％（52／59），特异度为77．78％（28／36），准确率为84．21％（80／95）；uE＋萤火虫微钙化增强技术诊断敏感度为95．08％（58／61），特异度为94．12％（32／34），准确率为94．74％（90／95），UE＋萤火虫微钙化增强技术诊断特异度高于二维超声、萤火虫技术、UE Itoh5分法（X2=5．141、4．026、4．026，P〈0．05），其准确率高于二维超声与萤火虫技术（X2=4．014、3．966，P〈0．05）。【结论】UE联合萤火虫微钙化增强技术对良恶性乳腺结节临床鉴别价值较高，有其较高的敏感度、特异度、准确率，可作为乳腺疾病筛查的有效手段。 [Objective]To analyze the clinical value of ultrasound elastography （UE） combined with microcalcifi- cation enhanced technique in differential diagnosis of benign and malignant breast nodules. [Methods] The clinical data of 80 cases of patients with breast masses （95 nodules） who were examined with ultrasound in the hospital during March 2013% February 2016 were retrospectively analyzed. All patients completed the two dimensional ultrasound, UE and ultrasound firefly microcalcification enhancement scanning. Pathological findings were used as controls, and the clinical value of UE combined with microcalcification enhanced technique in differential diagnosis of benign and malignant breast nodules was analyzed. [Results] The sensitivity, specificity and accuracy of two dimensional ultra- sound in differential diagnosis of benign and malignant breast nodules were 85.19% （46/54）, 65.85% （27/41） and 76.84 % （73/95）, respectively, while those of ultrasound firefly microcalcification enhanced technique were 85.71% （54/68）, 77.78% （21/27） and 78.95% （75/95）, respectively, those of UE Itoh 5 method were 88.14% （52/59）, 77.78% （28/36） and 84.21% （80/95）, respectively, and those of UE＋fireily microcalcification enhanced technique were 95.08% （58/61）, 94.12% （32/34） and 94.74% （90/95）, respectively. The diagnostic specificity of UE＋fire- fly microcalcification enhanced technique was higher than that of two dimensional ultrasound, firefly technique or UE Itoh 5 method （X2 = 5.141, 4.026, 4.026, P〈0.05）, and its accuracy was higher than that oftwo dimensiona ultrasound or firefly technique （X2= 4.014, 3.966, P〈0.05）. [Conclusion]The combination of UE and firefly micro cal- cification enhancement technique has higher clinical value in identifying benign and malignant breast nodules, and has higher sensitivity, specificity and accuracy. It can he used as an effective means for screening breast diseases.

关 键 词： 弹性成像技术 乳腺肿瘤 超声检查 诊断 鉴别 回顾性研究