作　　者： ;

机构地区： 中山大学

出　　处： 《中华器官移植杂志》 2015年第7期411-416,共6页

摘　　要： 目的 研究近年来国家自然科学基金委员会（NSFC）对我国器官移植领域的资助情况及其促进论文产出情况,并分析项目研究方向以展示器官移植的研究现状与热点.方法 全面收集1998-2014年NSFC资助项目信息以及项目发表的科学引文索引（SCI）论文信息.统计资金投入指标包括资助项目数、资助总金额和单个项目资助金额,论文产出指标包括论文总数、总被引次数、篇被引次数、H指数、篇投入资金.项目研究方向根据项目标题、摘要及主题词判定.结果 NSFC的资助项目数、资助总金额从1998年的7项155万元逐年增加,2011年达到了顶峰,为78项4274.7万元,后至2014年资助项目和总金额有所下降,但总体处于平台期;1998-2014年间单项资助金额中位数增加38万元.1998-2010年,项目发表SCI文章数量和总被引次数在上升,H指数逐年递增,2005年后明显增加,往后波动在13～19之间.2004年起,每篇SCI论文投入资金不超过11万.免疫调节与免疫耐受、缺血再灌注损伤及炎症反应、免疫排斥这3个方向的资助金额在所有研究方向中一直占主要部分;人造器官及异种移植方向资助金额年分布极不均匀;2011年起干细胞相关研究资助金额逐年递增.结论 在器官移植领域,研究投入对产出至关重要,继续加大资助力度将会催生更多高水平的研究成果,促使我国器官移植研究达到国际一流水平. Objective To summarize the funding of scientific research projects on solid organ transplantation by National Natural Science Foundation of China （NSFC） from 1998 to 2014 as well as the publications produced by these projects, and to display the hotspots of scientific research on solid organ transplantation.Method A systemic search was performed for the information of projects supported by NSFC from 1998 to 2014 and their papers published in Science Citation Index （SCI） journals.The indicators for analysis included the number of projects, total investment, average investment in each project, the number of papers published in SCI journals, total number of citations, average number of citations of each paper, H index and average investment in each paper.The research direction of each project was decided based on title, summary and key words provided by the profile of each project.Result The total investment on solid organ transplantation by NSFC was 1.55 million with a total of seven projects.It increased year by year and reached the peak in 2011.The investment in 2011 was 42.7 million yuan RMB with a total of 78 projects.The investment and number of projects remained stable after 2011.The median investment in each project was increased by 380 thousand yuan RMB from 1998 to 2014.From 1998 to 2010, the number of papers and total number of citations increased.H index increased steadily and slowly before 2005, followed by a surge in 2005.It stayed stable between 13 and 19 from 2005 to 2010.Investment in each SCI paper had never exceeded 110 thousand since 2004.Through analysis of research direction of all the projects, we found that the investment in the research projects on immune regulation and immune tolerance,ischemia-reperfusion injury and inflammation and immune rejection dominated total investment from 1998 to 2014.Investment in the research projects on artificial organs and xenotransplantation was distributed unevenly.Projects associated with stem cell had received increasing investment.Conclusion The

关 键 词： 器官移植 H指数 资助 产出 干细胞

分 类 号： [R9-1]

领　　域： []