导　　师： 徐晓阳

学科专业： D0302

授予学位： 硕士

作　　者： ;

机构地区： 华南师范大学

摘　　要： 该研究以sd大鼠为研究对象,以低压氧舱模拟2300±50m高原环境,通过模拟高原训练和补充大鼠需要量5倍的ve,观察大鼠血清超氧化歧化酶(sod)活性、血清丙二醛(mda)含量以及骨骼肌乳酸脱氢酶(ldh)和苹果酸脱氢酶(mdh)活性的变化,探讨模拟高原训练和ve干预对大鼠抗氧化能力及能量代谢有关酶的影响,为高原训练提供理论依据.该研究将sd大鼠随机分成6组:平原安静组(a组)、平原训练组(b组)、高原安静组(c组)、高原训练组(d组)、高原ve需要量5倍组(e组)、高原ve需要量5倍训练组(f组). With the development of the altitude training, these terms, such as the altitude stress, living high - training low, mimic altitude training have become popular topic within athletes, coaches and researchers. According to a large quantity of present research data in this area, we can see that people focus their attention on the means and environment of altitude training, however, they seldom pay close attention to the attitude nutrition. The main difference between the high-altitude environment and the low-altitude environment is the lack of oxygen, which exerts great influence on all systems and metabolizability of organism. The biggest problem of altitude training will face with is how to fight the lack of oxygen. Vitamin E is one of the important antioxidant substances in the body, which can improve the physiologic function and the material metabolism. Vitamin E will also be helpful to enhance aerobic staying - power and the training level in the altitude training, therefore athletes can take some VE to resist the lack of oxygen when they are training on plateau. The research' s purpose is to confer the effects of mimic altitude training and the VE supplement in SD rats. The research tested the following index: the activity of superoxide dismutase /(SOD/), malondiadehyde /(MDA/), the aerobic enzyme MDH activity of skeletal muscles and the anaerobic enzyme LDH activity of skeletal muscles. The research object is SD rats which have been divided six group: plain contrast /(A group/), plain training /(B group/), altitude contrast /(C group/), altitude training /(D group/), altitude 5 times VE supplied /(E group/), altitude training and 5 times VE supplied /(F group/). Result of this study shows: 1. The activity of body SOD is significantly higher than plain control /(A group/) and plain training /(B group/) after four weeks altitude training /(p<0.01/), the concentration of MDA is significantly lower than plain control /(A group/) and plain training/(B group/) /(p<0. 01/

关 键 词： 高原训练 干预 抗氧化 自由基 骨骼肌 有氧代谢酶 无氧代谢酶

领　　域： [文化科学] [文化科学]