作　　者： ; ; ;

机构地区： 郧阳师范专科学校化学系

出　　处： 《合成化学》 2004年第4期378-380,J003,共4页

摘　　要： 以肉桂酸为原料 ,经两步反应合成肉桂酸苄酯。第一步将肉桂酸制成肉桂酰氯 ,第二步将肉桂酰氯与苄醇反应制得肉桂酸苄酯。结构经IR ,1HNMR和MS确证。制备肉桂酰氯的最佳反应条件为 :肉桂酸2 4 0mmol,n(肉桂酸 )∶n(亚硫酰氯 ) =1.0 0∶1.0 8,反应温度 6 0℃ ,反应时间 30min。制备肉桂酸苄酯的最佳反应条件为 :肉桂酰氯 2 30mmol,n(肉桂酰氯 )∶n(苄醇 ) =1.0∶1.2 ,反应温度 15℃～ 2 0℃ ,反应时间 1.5h ,产率在 Benzyl cinnamate was synthesized by a two-step reaction: cinnamic acid reacted with thionyl chloride giving cinnamyl chloride and cinnamyl chloride was then reacted with benzyl alcohol giving benzyl cinnamate whose structure was characterized by IR, 1H NMR and MS. For first step reaction, cinnamic acid was 240mmol, the molar ratio of cinnamic acid to thionyl chloride was 1.00 ∶1.08, reaction temperature was 60℃, the reaction time was 30min, and the residual thionyl chloride was removed by vacuum distillation. For second step reaction, cinnamyl chloride was 230mmol, the molar ratio of cinnamyl chloride to benzyl alcohol was 1.0 ∶1.2, reaction temperature was 10℃～15℃, the reaction time was 1.5h. The yield was over 92%.

关 键 词： 肉桂酰氯 肉桂酸苄酯 合成

领　　域： [理学] [理学] [理学] [理学]