机构地区: 广西大学化学化工学院化学系
出 处: 《天然产物研究与开发》 2004年第3期201-203,共3页
摘 要: 首次从大戟科植物珠子草中分离得到软木三萜酮。利用晶体X -射线法与一维和二维核磁共振法测定了该化合物的结构 ,指认了核磁共振信号的归属。晶体衍射结果表明 ,化合物是以斜方晶体空间群形成晶体 ,晶体数据维P2 (1) 2 (1) 2 (1)witha =6 36 1(2 ) ,b=13 933(3) ,c=2 8 4 4 0 (6 ) ,α =90° ,β =90°,γ=90° ,V =2 5 2 0 6 (11) 3 ,Z =4 在晶体中存在一个微弱的分子间的作用力C H O =C ,此作用力被认为是晶体形成的重要因素。NMR方法确定化合物的结构相同 ,表明了软木三萜酮在晶体和溶液具有相同的构型。 Friedelin was first isolated from Phyllanthus niruri linn.Its structure was determined by means of spectroscopy methods and X-ray crystallography.Chemical shifts of all carbons and protons were assigned based on the 2D NMR methods.The structure elucidated by means of NMR coincided with the structure got from X-ray diffraction method.It means that structure of friedelin in crystal an in solution have a same configuration.This compound crystallized in the orthorhombic space group P2(1)2(1)2(1) with a= 6.361(2)*!,b=13.933(3)*!,c=28.440(6)*!,α=90°,β=90°,γ=90°,V=2520.6(11)*! 3,Z=4.A slightlyintermolecular contact C-H ..... O=C was observed firstly in this crystal.This contact was supposed to be the determinative factor of formation of the crystal.
关 键 词: 珠子草 软木三萜酮 晶体结构 核磁共振 大戟科植物
领 域: [生物学]