作　　者： ; ; ; ; ;

机构地区： 华南农业大学动物科学学院

出　　处： 《实验生物学报》 2004年第1期67-71,共5页

摘　　要： 组织工程是一门新兴的边缘学科,它是利用体外培养的人体功能细胞与适当的细胞外基质或支架材料相结合,然后将其移植到体内病损部位以期达到修复目的. In order to investigate the biocompatibility, degradation and inflammatory reactions of poly benzyl glutamate (PBLG), poly lactie-co-glycolic acid (PLGA) and fibrin gel used as the scaffolds co -cultured with the hepatocytes of rats under simulated microgravity conditions in rotating wall vessel bioreactor (RWVB). PLGA is low biocompatibility, PBLG is medium biocompatibilty with rat hepatocytes. Fibrin gel is high biocompatibility, no toxic degradation and no inflammatory reactions. Fibrin gel can be used as three dimensional scaffolds of rat hepatocytes under simulated microgravity.

关 键 词： 模拟微重力 三维培养 肝细胞 大鼠 支架材料 细胞亲合性

领　　域： [生物学]