作　　者： ; ; ; ; ; ; ;

机构地区： 华南理工大学材料科学与工程学院生物材料研究所

出　　处： 《电子显微学报》 2003年第4期304-310,共7页

摘　　要： 本文利用溶胶 凝胶法制备了CaO P2 O5 SiO2 系统生物活性玻璃 ,并以其为原料制备了用于骨修复及骨组织工程支架的块状生物活性材料。利用体外实验方法 (invitro)结合X射线衍射 (XRD)、扫描电子显微镜 (SEM)和傅立叶变换红外光谱分析 (FTIR)技术对不同烧结工艺制备的材料结构、晶相和生物活性的影响进行了分析研究。研究表明 ,经 80 0℃和 110 0℃烧结 5min的两种材料均有硅磷酸钙Ca5(PO4 ) 2 SiO4 微晶相析出。烧结温度越高 ,析出微晶相的体积比例越大 ,材料的生物活性则越低。在模拟生理溶液中碳酸羟基磷灰石 (HCA)只在烧结体中的玻璃颗粒表面形成 ,而在其硅磷酸钙Ca5(PO4 ) 2 SiO4 微晶相表面未发现HCA形成。 Two bioactive porous materials were prepared from sol gel derived bioglass powder in the system CaO P 2O 5 SiO 2. The microstructure, crystal phases and bioactivity of the materials with different heat treatment programs were investigated via in vitro method and XRD, SEM and FTIR techniques. It was indicated that crystals of calcium phosphate silicate (Ca 5(PO 4) 2SiO 4) had precipitated in both samples which were heat treated at temperatures 800℃ and 1100℃ for 5 minutes respectively. The higher temperature for heat treatment, the higher volumetric ratio of the crystal phase to the glass phase, and the lower bioactivity of the material since hydroxy carbonate apatite (HCA) crystallites only formed on the surface of the glass particles in the structure of the materials. No HCA crystal was found on the surface of calcium phosphate silicate crystals.

关 键 词： 溶胶 凝胶法 生物活性玻璃 生理溶液 碳酸羟基磷灰石 扫描电子显微镜 射线衍射 红外光谱分析 材料结构

领　　域： [化学工程] [化学工程] [一般工业技术]