作　　者： ; ;

机构地区： 郧阳师范高等专科学校化学系

出　　处： 《化学试剂》 2003年第6期347-349,共3页

摘　　要： 研究了应用烯基膦亚胺与芳基异氰酸酯、醇的串联aza-Wittig反应合成2-烷氧基-3芳基-5-苯基亚甲基-4H-咪唑啉-4-酮衍生物的新方法。探讨了反应进行的条件和产物的波谱性质,提出了可能的环化反应机理。生成的环化产物结构经元素分析、IR、1HNMR和MS确证。对这些新型杂环化合物的杀菌活性测试结果表明,部分化合物表现出较好的抑菌活性。 2-Alkoxy-3-aryl-5-phenylmethylidene-4H-imid-azolin-4-ones were synthesized via tandem aza-Wittig reaction of vinyliminophosphorane , aromatic isocyanate and alcohols. The reaction condition and the spectral properties of cyclized compounds were researched,and a possible mechanism for the cyclization reaction was put forward. All the cyclized products were new, and their structures were confirmed by elemental analysis,IR, HNMR and MS. The fungicidal activities of the new heterocyclics synthesized were studied, and their results showed that some of the compounds exhibited good fungicidal activities.

关 键 词： 烷氧基 芳基 苯基亚甲基 咪唑啉 酮衍生物 合成 杀菌活性 杂环化合物 杀菌剂 线粒体呼吸抑制剂

领　　域： [化学工程]