作　　者： ; ; ;

机构地区： 华南理工大学食品与生物工程学院

出　　处： 《广州食品工业科技》 2003年第B11期38-40,35,共4页

摘　　要： 针对双歧杆菌活菌制剂在口服时,不耐受强胃酸,活性菌在有氧条件下容易失活,常温下保存期短等存在问题,将微型包囊技术应用于微生态制剂中,并已研制成活性双歧联菌株耐酸肠溶微囊微生态制剂,获得较理想的效果。本文介绍了双歧联菌株混合培养工艺条件的优化研究,活性双歧杆菌冻干保护剂和冻干条件的确定,微型包囊复合囊材配方的优化研究,最佳微型包囊方法的确定及微囊化条件的研究,含活性菌微囊的耐酸肠溶试验,含活性菌微囊的保存稳定性试验,50升发酵罐中试结果,以及活性双歧联菌株微囊微生态制剂的研制等。 There are some problems. For example, the viable Bifidobacterium agents have been deactivated when taken orally or passed through the stomach; the shelf life is short when they have been kept in the normal temperature. In order to settle these problems, we have developed the micro- ecological agent of the viable associated Bifidobacterium, which endured the high stomach acidity and got some good effect. In this paper, we introduce the study on the optimization with stimulated culture of the viable associated Bifidobacterium, the confirmability of the cryoprotectant and conditions for the freeze-dried, the study on the optimization of the formula of the micro-encapsulation complex wall materials, the confirmability of the optimization of micro-encapsulation and the study on the condition of micro-encapsulation, the experiment of endured the high stomach acidity and the conservative stabilization, the result of 50l ferment, the development of the micro-ecological agent of the viable associated Bifidobacterium.

关 键 词： 微型包囊技术 双歧联菌株 混合培养 工艺优化 微生态制剂

领　　域： [化学工程]