作　　者： ; ; ; ; ;

机构地区： 暨南大学生命科学技术学院化学系

出　　处： 《天然产物研究与开发》 2003年第5期393-395,397,共4页

摘　　要： 从中国南海棕色扁海绵Phakellia fusca Schimidt的乙醇浸提物中,分离得到3个吡咯生物碱,结合理化性质,波谱分析,文献检索,确定其结构分别为4,5-二溴-1 H-吡咯-2-甲酸甲酯(1)、4,5-二溴-3-氰-1 H-吡咯-2-甲酸甲酯(2)、4,5-二溴-1 H-吡咯-2-甲酰氨(3)。其中化合物(2)未见文献报道。 Three brominated alkaloids (1-3) were isolated from the marine sponge Phakellia fusca Schimidt. Their structures determined as: 4, 5-dibromo-1H-pyrrole-2-carboxylic acid methyl ester 1, 4, 5-dibromo-3-cyano-1H-pyrrole-2-carboxylic acid methyl ester 2, 4, 5-dibromo-1H-pyrrole-2-carboxylic acid amide 3, respectively on the basis of the data of GC-MS and some other spectrometric methods. These pyrroles were found for the first time in the marine sponge P. fusca Schmidt. The finding of those alkaloids is of considerable value for chemotaxonomy of the Axinellidae family and compound 2 is a new compound.

关 键 词： 海绵 棕色扁海绵 化学成分 生物碱 气 质联用

领　　域： [生物学]