作　　者： ; ; ;

机构地区： 徐州师范大学体育学院

出　　处： 《体育与科学》 2000年第3期29-33,共5页

摘　　要： SD大鼠24只随机分为2组：1，安静组（C组）2．训练组（T组）。实验结果表明：1．实验前后一般情况的变化：6周大强度训练后T组大鼠体重增长率、饮食增长率、血浆中Hb都明显低于C组（P＜0．01）；而T组血浆中WBC值明显高于C组（P＜0．01）；训练过程中T组大鼠运动能力明显下降，训练后表现出倦怠、反应迟钝、双目无神、毛发杂乱无光泽等较差的精神状况，特别是训练后期这种变化更为突出。2．运动训练对下丘脑、垂体和血浆神经肽的影响1）．T组大鼠下丘脑中β-EP含量明显高于C组（P＜0．001）；垂体水平的β-EP含量，T组明显低于C组，但无统计学意义（P＞0．05）；在血浆中β-EP含量，T组明显高于其他C组（P＜0．05）。2）．下丘脑中DynAl-13含量，T组明显高于C组（P＜0．01）。垂体中DynAl-13含量，T组明显高于C组（P＜0．01)，血浆中DynAl-13含量，T组高于C组但无统计学意义（P＞0．05）。综上所述：不难看出6周大强度游泳训练可以导致大鼠下丘脑、垂体和血浆中神经肽合成及分解功能异常，提示长时间大强度运动可以引起神经内分泌系统机能的紊乱，神经内分泌调节中枢─—下丘脑功能失调在其中起了关键作用；试验结果提示我们在训练过程中，要重视神经内分泌系统调节机能在机体疲劳发生过程中的作用和地? Regulation function of neuroendocrine system is crucial in maintenance of body internal environment balance during exercise. The purpose of the present investigation was to determine the changes of centain neuropeptides in hypothalamus, pituitary and plasma in rats after heavy-load training of 6 weeks, to probe into the alteration principles of neuroendocrine system after strenuous exercise.24 SD male rats were randomly divided into groups as follows: 1. rest control group(C);2. training group (T), the results obtained are as follows: 1) After strenuous exercise for 6 weeks,the increasing rates body weight and food consumption for T rats were significantly lower than that of C. respectively, Hb content demonstrated the same tendency (p ＜ 0. 01 ),whereas WBC level for rats of T rats was obviously higher than that of C (p ＜ 0. 01 ). 2)Concentration of β-EP in hypothalamus of T rats was significantly higher than C (p ＜ 0.001 ); as for the pituitary level of β-EP, the former was lower than the latter, yet demonstrating no statistic signilificance. The plasma content of β-EP was significantly higher in T than in C (p ＜ 0. 05 ). 3) The Dyn-13 levels in hypothalamus and pituitary of T rats were all bigher significantly than those of C (p ＜0. 01 ).In sum, prolonged swimming exercise of 6 weeks can result in malfunction of neuropeptides in hypothalamus, pituitary and plasma.

关 键 词： 运动强度 下丘脑 垂体 血浆 神经内分泌 神经肽

领　　域： [文化科学] [文化科学]