作　　者： ; ; ; ; ;

机构地区： 湖南大学化学化工学院

出　　处： 《应用化学》 2003年第2期195-197,共3页

摘　　要： Acetyl-5-bromo-6-methoxynaphthalene(1) was hydrogenated over Pd/C by bubbling H 2 into a mixture of n-BuOH, KOH(aq) and CTAB. The effects of the concentration of KOH and n(1)∶ n(Pd)∶ n(CTAB) on the hydrogenation were investigated. Bubbling H 2 for 4.25 h at 60 ℃ into the mentioned mixture solution gave 6-methoxy-2-naphthylethanol in yield of 95.7%. Acetyl-5-bromo-6-methoxynaphthalene(1) was hydrogenated over Pd/C by bubbling H 2 into a mixture of n-BuOH, KOH(aq) and CTAB. The effects of the concentration of KOH and n(1)∶ n(Pd)∶ n(CTAB) on the hydrogenation were investigated. Bubbling H 2 for 4.25 h at 60 ℃ into the mentioned mixture solution gave 6-methoxy-2-naphthylethanol in yield of 95.7%.

关 键 词： 乙酰基 溴 甲氧基萘 多相催化氢化 甲氧基萘基乙醇 萘普生 药物中间体

领　　域： [化学工程]