机构地区: 佛山科学技术学院生命科学学院动物医学系
出 处: 《中国预防兽医学报》 2003年第1期44-46,共3页
摘 要: 用不同毒力株鸭肝炎病毒人工感染雏鸭 ,分别于 1、3、5、7天测定雏鸭肝组织中超氧化物歧化酶 (SOD)和谷胱甘肽过氧化物酶 (GSH_Px)的活性 ,研究SOD和GSH_Px在鸭病毒性肝炎 (DVH)发病过程中的作用。结果表明 ,雏鸭感染不同毒力株鸭肝炎病毒后 1天 ,肝组织匀浆中的SOD和GSH_Px活性均下隆 ;3天时弱毒株组 ( 1 78.1 9± 1 7.5 9) ,和中毒株组 ( 1 65 .73± 1 7.2 1 )肝组织中SOD活性都显著低于对照组 ( 1 98.0 2± 8.64) ,强毒株组 ( 1 5 5 .1 1± 1 4.3 4)则极显著低于对照组 ;5天时实验组肝组织中SOD和GSH_Px活性均显著或极显著低于对照组。 Liver SOD and GSH-Px activity were measured in Young ducks after infection 1d?3d?5d?7d with different toxic strains of duck hepatitis virus(DHV).Results indicated that SOD and GSH-Px activity in infected group were apparent lower than that of control group at 1d,then Liver SOD activity apparent lower in weak toxic strain group(178.19±17.59)?middle toxic strain group(165.73±17.21)and strong toxic strain group(155.11±14.34)than that of control group (198.01±8.64)at 3d.Liver SOD and GSH-Px activity in infected group were apparent or extremely lower than that of control group at 5d.It suggests that free radical may participate the pathologic process of DVH.