作　　者： ; ; ;

机构地区： 暨南大学生命科学技术学院化学系

出　　处： 《精细化工》 2013年第3期313-319,共7页

摘　　要： 以亮氨酸和苯丙氨酸为起始原料,改变其环合位点,优化其合成路线,合成了两个Galaxamide环五肽类似物,其环合收率近50%。使用反相HPLC进行分离纯化,通过1HNMR、13CNMR和MS对其结构进行表征。 With leucine and phenylalanine as starting materials, two new pentapeptides were totally synthesized through changing the cyclic sites and optimizing the route of synthesis. The yield of cyclization reaction was up to 50%. The products were isolated and purified by RP-HPLC, and the compound structures were characterized by means of ^1HNMR,^ 13 CNMR and MS.

关 键 词： 环五肽 环合 海洋生物环肽 医药与日化原料

领　　域： [化学工程] [理学] [理学]