作　　者： ; ; ; ; ; ;

机构地区： 河北医科大学药学院

出　　处： 《理化检验（化学分册）》 2012年第7期760-762,772,共4页

摘　　要： 在磷酸、硼酸及乙酸组成的缓冲介质中,齐墩果酸与β-环糊精反应生成包合络合物,其包合摩尔比为1比1。包合物的激发波长及发射波长的峰分别位于355nm及404nm处,在25℃条件下的结合常数为71L.mol-1,还测定了反应的热力学参数。测得ΔH0与ΔS0均大于0,说明此包合反应为吸热反应。测得ΔG0值小于0,且随反应温度升高而变得更负,说明此反应在试验条件下能自发进行,而随反应温度的升高,反应的自发性增强。 It was found that in a buffer solution of H3PO4-H4 BO3-HOAe, an inclusion complex was formed between oleanic acid （OLA） and fi-cyclodextrin （β-CD） with mole ratio of 1 to 1. Excitation and emission maxima of the complex were found at wavelengths of 355 nm and 404 nm respectively. Value of association constant found at 25 ℃ was 71 L .mol^-1, thermodynamic parameters of the complex were also determined. Values of △H^0 and △S^0 were both shown to be greater than 0, which proved that the inclusion reaction was endothermic. Value of △G^0 was found to be smaller than 0, and becoming smaller as the reaction temperature increases, which proved that the inclusion reaction proceeds spontaneously and that the spontaneity of the reaction increases with the raise of reaction temperature.

关 键 词： 荧光光谱法 包合物 齐墩果酸 环糊精 热力学参数

领　　域： [理学] [理学]