作　　者： ; ; ; ; ;

机构地区： 广州中医药大学体育健康学院

出　　处： 《体育学刊》 2012年第2期138-141,共4页

摘　　要： 为了探讨高强度训练对SD大鼠OAH品质的提高,将30只SD大鼠随机分为训练干预组与安静对照组。训练干预组以坡度10%、28 m/min、每次60 min、每天1次、每周5 d条件下于跑台上运动8周;安静对照组不施加运动干预措施。在最后一次训练结束72 h即刻进行腓肠肌与血清的取材。检测指标为骨骼肌与血清的丙二醛(malondialdehyde,MDA)、总超氧化物歧化酶(total super oxide dismutase,TSOD)、过氧化氢酶(catalase,CAT)和还原型谷胱甘肽(reduced glutathione,RGSH)。结果发现:骨骼肌与血清中的RGSH含量和TSOD活性显著性增高;MDA在血清中显著性降低,但在骨骼肌中显著性升高;CAT活性在血清中显著性增高,但在骨骼肌中不变。实验表明:高强度训练能够实现SD大鼠OAH升级。 In order to probe into the enhancement of the quality of oxidant-antioxidant homeostasis （OAH） by high intensity exercising, the authors divided 30 SD rats randomly into a training intervention group and a calm control group. The rats in the training intervention group ran on a treadmill for 8 weeks under such conditions as 10% slope, 28m/rain, 60min/time, 1 time/day, 5 days/week, while no exercising intervention measure was taken for the rats in the calm control group. Gastrocnemius muscle and blood serum were sampled at 72h after the last round of training. The test indexes were malondialdehyde （MDA）, total superoxide dismutase （TSOD）, catalase （CAT） and reduced glutathione （RGSH） in skeletal muscle and blood serum. The authors revealed the following findings： the content of RGSH and the activity of TSOD in skeletal muscle and blood serum increased significantly; MDA decreased significantly in blood serum, but increased significantly in skeletal muscle; the activity of CAT increased significantly in blood serum, but remained unchanged in skeletal muscle. The experiment indicated that high intensity training can realize the enhancement of OAH of SD rats.

关 键 词： 运动生物化学 氧化还原 内稳态 高强度运动 大鼠

领　　域： [文化科学] [文化科学]