机构地区: 中国海洋大学医药学院海洋药物教育部重点实验室
出 处: 《有机化学》 2011年第10期1553-1562,共10页
摘 要: 2-氨基-2-脱氧-D-葡萄糖广泛分布在有机生物体中,在糖化学及糖生物学上受到越来越多的重视.综述了2005年以来化学合成氨基葡萄糖氧苷的新进展,主要包括异头碳活化基团、氨基保护基以及糖苷化催化剂的应用. 2-Amino-2-deoxyglucose which is widely distributed in organisms is becoming more and more important in glycochemistry and glycobiology.The recent studies of the chemical synthesis of O-glycosides of glucosamine are reviewed,mainly focusing on some new application of anomeric leaving groups,pro-tecting groups and promoters.